254623

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2427775..2427959 Replicon chromosome
Accession NZ_CP102955
Organism Staphylococcus aureus strain 28-G-I

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW961_RS11980 Protein ID WP_000482647.1
Coordinates 2427852..2427959 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2427775..2427835 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW961_RS11965 (NW961_11965) 2423305..2423472 - 168 WP_031860495.1 hypothetical protein -
NW961_RS11970 (NW961_11970) 2423703..2425436 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
NW961_RS11975 (NW961_11975) 2425461..2427224 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2427775..2427835 + 61 - - Antitoxin
NW961_RS11980 (NW961_11980) 2427852..2427959 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW961_RS11985 (NW961_11985) 2428093..2428479 - 387 WP_000779347.1 flippase GtxA -
NW961_RS11990 (NW961_11990) 2428737..2429879 + 1143 WP_001176863.1 glycerate kinase -
NW961_RS11995 (NW961_11995) 2429939..2430598 + 660 WP_000831298.1 membrane protein -
NW961_RS12000 (NW961_12000) 2430780..2431991 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW961_RS12005 (NW961_12005) 2432114..2432587 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254623 WP_000482647.1 NZ_CP102955:c2427959-2427852 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254623 NZ_CP102955:2427775-2427835 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References