254621

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2141171..2141368 Replicon chromosome
Accession NZ_CP102955
Organism Staphylococcus aureus strain 28-G-I

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW961_RS10500 Protein ID WP_001802298.1
Coordinates 2141264..2141368 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2141171..2141209 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW961_RS10475 (NW961_10475) 2137346..2138011 - 666 WP_001024095.1 SDR family oxidoreductase -
NW961_RS10480 (NW961_10480) 2138163..2138483 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW961_RS10485 (NW961_10485) 2138485..2139465 + 981 WP_258412249.1 CDF family zinc efflux transporter CzrB -
NW961_RS10490 (NW961_10490) 2139731..2140822 + 1092 WP_258415634.1 transcriptional regulator -
NW961_RS10495 (NW961_10495) 2141151..2141225 + 75 Protein_2024 hypothetical protein -
- 2141171..2141209 + 39 - - Antitoxin
NW961_RS10500 (NW961_10500) 2141264..2141368 - 105 WP_001802298.1 hypothetical protein Toxin
NW961_RS10505 (NW961_10505) 2142048..2142206 + 159 WP_001792784.1 hypothetical protein -
NW961_RS10510 (NW961_10510) 2142864..2143721 - 858 WP_000370929.1 HAD family hydrolase -
NW961_RS10515 (NW961_10515) 2143789..2144571 - 783 WP_258415635.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254621 WP_001802298.1 NZ_CP102955:c2141368-2141264 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254621 NZ_CP102955:2141171-2141209 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References