Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2140806..2141068 Replicon chromosome
Accession NZ_CP102954
Organism Staphylococcus aureus strain 30-P-10

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW951_RS10435 Protein ID WP_001802298.1
Coordinates 2140964..2141068 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2140806..2140969 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW951_RS10410 (NW951_10410) 2137046..2137711 - 666 WP_001024095.1 SDR family oxidoreductase -
NW951_RS10415 (NW951_10415) 2137863..2138183 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW951_RS10420 (NW951_10420) 2138185..2139165 + 981 WP_258412249.1 CDF family zinc efflux transporter CzrB -
NW951_RS10425 (NW951_10425) 2139431..2140522 + 1092 WP_258412250.1 transcriptional regulator -
- 2140806..2140969 + 164 - - Antitoxin
NW951_RS10435 (NW951_10435) 2140964..2141068 - 105 WP_001802298.1 hypothetical protein Toxin
NW951_RS10440 (NW951_10440) 2141748..2141906 + 159 WP_001792784.1 hypothetical protein -
NW951_RS10445 (NW951_10445) 2142564..2143421 - 858 WP_258412251.1 HAD family hydrolase -
NW951_RS10450 (NW951_10450) 2143489..2144271 - 783 WP_258412252.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254612 WP_001802298.1 NZ_CP102954:c2141068-2140964 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT254612 NZ_CP102954:2140806-2140969 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAACCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References