Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2115809..2116006 Replicon chromosome
Accession NZ_CP102952
Organism Staphylococcus aureus strain 39-B-49

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW967_RS10240 Protein ID WP_001802298.1
Coordinates 2115902..2116006 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2115809..2115847 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW967_RS10215 (NW967_10215) 2111993..2112658 - 666 WP_001024095.1 SDR family oxidoreductase -
NW967_RS10220 (NW967_10220) 2112810..2113130 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW967_RS10225 (NW967_10225) 2113132..2114112 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
NW967_RS10230 (NW967_10230) 2114378..2115469 + 1092 WP_258411245.1 transcriptional regulator -
NW967_RS10235 (NW967_10235) 2115789..2115863 + 75 Protein_1972 hypothetical protein -
- 2115809..2115847 + 39 - - Antitoxin
NW967_RS10240 (NW967_10240) 2115902..2116006 - 105 WP_001802298.1 hypothetical protein Toxin
NW967_RS10245 (NW967_10245) 2116686..2116844 + 159 WP_001792784.1 hypothetical protein -
NW967_RS10250 (NW967_10250) 2117502..2118359 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NW967_RS10255 (NW967_10255) 2118427..2119209 - 783 WP_258411246.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254591 WP_001802298.1 NZ_CP102952:c2116006-2115902 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT254591 NZ_CP102952:2115809-2115847 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References