Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1829026..1829208 Replicon chromosome
Accession NZ_CP102952
Organism Staphylococcus aureus strain 39-B-49

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag NW967_RS08660 Protein ID WP_001801861.1
Coordinates 1829026..1829121 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1829149..1829208 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW967_RS08625 (NW967_08625) 1824696..1825322 + 627 WP_045177256.1 hypothetical protein -
NW967_RS08630 (NW967_08630) 1825363..1825704 + 342 WP_045177258.1 DUF3969 family protein -
NW967_RS08635 (NW967_08635) 1825805..1826377 + 573 WP_045177260.1 hypothetical protein -
NW967_RS08640 (NW967_08640) 1826575..1827203 - 629 Protein_1697 ImmA/IrrE family metallo-endopeptidase -
NW967_RS08645 (NW967_08645) 1827506..1827682 - 177 WP_000375477.1 hypothetical protein -
NW967_RS08650 (NW967_08650) 1827693..1828076 - 384 WP_000070811.1 hypothetical protein -
NW967_RS08655 (NW967_08655) 1828680..1828823 - 144 WP_001549059.1 transposase -
NW967_RS08660 (NW967_08660) 1829026..1829121 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1829149..1829208 - 60 - - Antitoxin
NW967_RS08665 (NW967_08665) 1829244..1829345 + 102 WP_001791893.1 hypothetical protein -
NW967_RS08670 (NW967_08670) 1829323..1829499 - 177 Protein_1703 transposase -
NW967_RS08675 (NW967_08675) 1829693..1830070 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1822136..1856718 34582


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T254587 WP_001801861.1 NZ_CP102952:1829026-1829121 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT254587 NZ_CP102952:c1829208-1829149 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References