Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2463057..2463241 Replicon chromosome
Accession NZ_CP102945
Organism Staphylococcus aureus strain SCAID OTT1-2022 (150)

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NW338_RS12395 Protein ID WP_000482647.1
Coordinates 2463134..2463241 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2463057..2463117 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW338_RS12380 2458587..2458754 - 168 WP_001792506.1 hypothetical protein -
NW338_RS12385 2458985..2460718 - 1734 WP_000486491.1 ABC transporter ATP-binding protein -
NW338_RS12390 2460743..2462506 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2463057..2463117 + 61 - - Antitoxin
NW338_RS12395 2463134..2463241 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NW338_RS12400 2463375..2463761 - 387 WP_000779347.1 flippase GtxA -
NW338_RS12405 2464019..2465161 + 1143 WP_001176863.1 glycerate kinase -
NW338_RS12410 2465221..2465880 + 660 WP_000831298.1 membrane protein -
NW338_RS12415 2466062..2467273 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW338_RS12420 2467396..2467869 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T254540 WP_000482647.1 NZ_CP102945:c2463241-2463134 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254540 NZ_CP102945:2463057-2463117 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References