Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2182446..2182662 Replicon chromosome
Accession NZ_CP102945
Organism Staphylococcus aureus strain SCAID OTT1-2022 (150)

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag NW338_RS10930 Protein ID WP_001802298.1
Coordinates 2182558..2182662 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2182446..2182501 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW338_RS10905 2178595..2179260 - 666 WP_001024089.1 SDR family oxidoreductase -
NW338_RS10910 2179412..2179732 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
NW338_RS10915 2179734..2180711 + 978 WP_000019733.1 CDF family zinc efflux transporter CzrB -
NW338_RS10920 2180977..2182068 + 1092 WP_000495669.1 hypothetical protein -
- 2182446..2182501 + 56 - - Antitoxin
NW338_RS10930 2182558..2182662 - 105 WP_001802298.1 hypothetical protein Toxin
NW338_RS10935 2183342..2183500 + 159 WP_001792784.1 hypothetical protein -
NW338_RS10940 2184158..2185015 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
NW338_RS10945 2185083..2185865 - 783 WP_072498841.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T254538 WP_001802298.1 NZ_CP102945:c2182662-2182558 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT254538 NZ_CP102945:2182446-2182501 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References