Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4099671..4100335 Replicon chromosome
Accession NZ_CP102780
Organism Pandoraea commovens strain LB-19-202-79

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NTU39_RS18470 Protein ID WP_150666484.1
Coordinates 4100057..4100335 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NTU39_RS18465 Protein ID WP_039397058.1
Coordinates 4099671..4099982 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTU39_RS18455 (NTU39_18455) 4096242..4097741 + 1500 WP_150666485.1 HDOD domain-containing protein -
NTU39_RS18460 (NTU39_18460) 4098273..4099643 + 1371 WP_150577008.1 nucleobase:cation symporter-2 family protein -
NTU39_RS18465 (NTU39_18465) 4099671..4099982 - 312 WP_039397058.1 HigA family addiction module antitoxin Antitoxin
NTU39_RS18470 (NTU39_18470) 4100057..4100335 - 279 WP_150666484.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NTU39_RS18475 (NTU39_18475) 4100467..4103790 - 3324 WP_150666483.1 error-prone DNA polymerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(27-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(21-66)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10655.27 Da        Isoelectric Point: 10.8371

>T254188 WP_150666484.1 NZ_CP102780:c4100335-4100057 [Pandoraea commovens]
MIENFKCRDTALLFSGRRVMRWRAVESAAMRKLQQLHAAATLSFLRAPPGNRLEALRGNRLGQYSIRINDQWRLCFRFDA
GTASDVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11294.20 Da        Isoelectric Point: 10.2163

>AT254188 WP_039397058.1 NZ_CP102780:c4099982-4099671 [Pandoraea commovens]
MTRQVPLATPGEILAQEWLGPMGISQYALAKAIDVPPRRINEIVLGKRAITVDTALRLGAFFGVDAQSWLNLQNQYDAEI
ARANMVDVLKTIKHRARALLAAA

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References