Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4359730..4360232 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name yoeB Uniprot ID A0A6P1S0U5
Locus tag NV347_RS19635 Protein ID WP_039482019.1
Coordinates 4359978..4360232 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag NV347_RS19630 Protein ID WP_039324900.1
Coordinates 4359730..4359981 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS19615 (NV347_19615) 4356130..4357089 + 960 WP_039512800.1 ABC transporter permease -
NV347_RS19620 (NV347_19620) 4357082..4357948 + 867 WP_039482013.1 ABC transporter permease -
NV347_RS19625 (NV347_19625) 4357945..4359654 + 1710 WP_039512799.1 ABC transporter ATP-binding protein -
NV347_RS19630 (NV347_19630) 4359730..4359981 + 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
NV347_RS19635 (NV347_19635) 4359978..4360232 + 255 WP_039482019.1 Txe/YoeB family addiction module toxin Toxin
NV347_RS19640 (NV347_19640) 4360274..4361128 - 855 WP_039482022.1 helix-turn-helix domain-containing protein -
NV347_RS19645 (NV347_19645) 4361153..4361992 - 840 WP_039482025.1 HTH-type transcriptional activator RhaS -
NV347_RS19650 (NV347_19650) 4362328..4363818 + 1491 WP_258210296.1 rhamnulokinase -
NV347_RS19655 (NV347_19655) 4363815..4365077 + 1263 WP_039482031.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10211.76 Da        Isoelectric Point: 8.0353

>T254137 WP_039482019.1 NZ_CP102749:4359978-4360232 [Pectobacterium parvum]
VKLIWSEEAWEDYLYWQDIDKRIVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT254137 WP_039324900.1 NZ_CP102749:4359730-4359981 [Pectobacterium parvum]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6P1S0U5

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References