254126

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 260367..261718 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name HipT Uniprot ID A0A6P1S2T8
Locus tag NV347_RS01105 Protein ID WP_039483287.1
Coordinates 260367..261407 (-) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID A0A6P1S6U4
Locus tag NV347_RS01110 Protein ID WP_039483284.1
Coordinates 261404..261718 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS01080 (NV347_01080) 257004..257393 + 390 WP_039513346.1 Mor transcription activator family protein -
NV347_RS01085 (NV347_01085) 257462..257821 - 360 WP_039483297.1 hypothetical protein -
NV347_RS01090 (NV347_01090) 257886..258488 - 603 WP_039483294.1 hypothetical protein -
NV347_RS01095 (NV347_01095) 258946..259851 + 906 WP_039483290.1 siderophore-interacting protein -
NV347_RS01100 (NV347_01100) 259939..260256 - 318 Protein_213 thiol:disulfide interchange protein DsbG -
NV347_RS01105 (NV347_01105) 260367..261407 - 1041 WP_039483287.1 HipA domain-containing protein Toxin
NV347_RS01110 (NV347_01110) 261404..261718 - 315 WP_039483284.1 HipA N-terminal domain-containing protein Antitoxin
NV347_RS01115 (NV347_01115) 261703..262029 - 327 WP_039483282.1 helix-turn-helix domain-containing protein -
NV347_RS01120 (NV347_01120) 262217..263350 - 1134 WP_039483273.1 alkylhydroperoxidase domain protein -
NV347_RS01125 (NV347_01125) 263347..264381 - 1035 WP_039483271.1 putative FMN-dependent luciferase-like monooxygenase -
NV347_RS01130 (NV347_01130) 264429..266090 - 1662 WP_165707380.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39676.76 Da        Isoelectric Point: 6.7797

>T254126 WP_039483287.1 NZ_CP102749:c261407-260367 [Pectobacterium parvum]
MIRCRILLTPLTHEEEIATGYSRKGLKHLTGSMHASSTLRFTRQQFMHDLPQAQKGMSISGYQPKIQMVLEERAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLRFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGSLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAECVESTYRDSFMP
ADAIETTLRCYRHRLKLMSILDAERI

Download         Length: 1041 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11868.62 Da        Isoelectric Point: 8.3774

>AT254126 WP_039483284.1 NZ_CP102749:c261718-261404 [Pectobacterium parvum]
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFHSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6P1S2T8

Antitoxin

Source ID Structure
AlphaFold DB A0A6P1S6U4

References