Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 137587..138441 Replicon chromosome
Accession NZ_CP102749
Organism Pectobacterium parvum strain YT22221

Toxin (Protein)


Gene name yhaV Uniprot ID A0A6P1S1D5
Locus tag NV347_RS00570 Protein ID WP_039487843.1
Coordinates 137587..138075 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A6P1S4C9
Locus tag NV347_RS00575 Protein ID WP_039487859.1
Coordinates 138100..138441 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NV347_RS00550 (NV347_00550) 134110..134778 + 669 WP_039487849.1 6-phosphogluconate phosphatase -
NV347_RS00555 (NV347_00555) 134798..135526 - 729 WP_039487847.1 amino acid ABC transporter permease -
NV347_RS00560 (NV347_00560) 135528..136271 - 744 WP_039487846.1 amino acid ABC transporter permease -
NV347_RS00565 (NV347_00565) 136552..137388 - 837 WP_039487845.1 ABC transporter substrate-binding protein -
NV347_RS00570 (NV347_00570) 137587..138075 - 489 WP_039487843.1 type II toxin-antitoxin system YhaV family toxin Toxin
NV347_RS00575 (NV347_00575) 138100..138441 - 342 WP_039487859.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
NV347_RS00580 (NV347_00580) 138774..139952 - 1179 WP_039487841.1 benzoate/H(+) symporter BenE family transporter -
NV347_RS00585 (NV347_00585) 140044..140610 + 567 WP_039487839.1 XRE family transcriptional regulator -
NV347_RS00590 (NV347_00590) 140671..141402 - 732 WP_039487837.1 phosphate signaling complex protein PhoU -
NV347_RS00595 (NV347_00595) 141415..142188 - 774 WP_039487836.1 phosphate ABC transporter ATP-binding protein PstB -
NV347_RS00600 (NV347_00600) 142275..143162 - 888 WP_039275952.1 phosphate ABC transporter permease PstA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

PrlF antitoxin

(15-113)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 18690.49 Da        Isoelectric Point: 6.8563

>T254125 WP_039487843.1 NZ_CP102749:c138075-137587 [Pectobacterium parvum]
MEYLDVNGWKICFHSCFLQQIAELAQKVVELKAAKPDEYLGKKETKLLHAIERVIEEWIAVDPLNPQYRQGDTLGDEFKH
WFRAKFLSQFRLFYRCSAEHKTIIIGWVNDFDTLRAYGSKTDAYKVFAGMLRAGEPPDDWEKLLNEAKAITATTSIPGFL
GK

Download         Length: 489 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12567.24 Da        Isoelectric Point: 4.4335

>AT254125 WP_039487859.1 NZ_CP102749:c138441-138100 [Pectobacterium parvum]
MAIQINTADVSLRAESRLTERSQTTIPAAIRDALHLKPGEYIKYTLLAGGKVIMSRQEEEQDDPVVSQFLTFLENDMKKN
PQNIHSIPVAFWESVKALTAGVEVDLDAPLTDD

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6P1S1D5

Antitoxin

Source ID Structure
AlphaFold DB A0A6P1S4C9

References