Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 616455..616940 Replicon chromosome
Accession NZ_CP102712
Organism Lacticaseibacillus rhamnosus strain DM054

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag NIM79_RS02900 Protein ID WP_230318488.1
Coordinates 616455..616562 (-) Length 36 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A807RQZ2
Locus tag NIM79_RS02905 Protein ID WP_005684270.1
Coordinates 616668..616940 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIM79_RS02885 (NIM79_002885) 611772..612608 - 837 WP_014569137.1 Rgg/GadR/MutR family transcriptional regulator -
NIM79_RS02890 (NIM79_002890) 612656..614071 - 1416 WP_015764852.1 IS5-like element ISLrh2 family transposase -
NIM79_RS02895 (NIM79_002895) 614822..616231 - 1410 WP_005684271.1 3'-5' exonuclease -
NIM79_RS02900 (NIM79_002900) 616455..616562 - 108 WP_230318488.1 type II toxin-antitoxin system YafQ family toxin Toxin
NIM79_RS02905 (NIM79_002905) 616668..616940 - 273 WP_005684270.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NIM79_RS02910 (NIM79_002910) 617053..617346 + 294 WP_005684269.1 metalloregulator ArsR/SmtB family transcription factor -
NIM79_RS02915 (NIM79_002915) 617428..618591 + 1164 WP_005684266.1 MFS transporter -
NIM79_RS02920 (NIM79_002920) 618745..619320 + 576 WP_014569140.1 DNA-3-methyladenine glycosylase I -
NIM79_RS02925 (NIM79_002925) 619442..619660 + 219 WP_014569141.1 hypothetical protein -
NIM79_RS02930 (NIM79_002930) 619789..620670 - 882 WP_005684263.1 class II fructose-1,6-bisphosphate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-30)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3997.68 Da        Isoelectric Point: 4.6219

>T254062 WP_230318488.1 NZ_CP102712:c616562-616455 [Lacticaseibacillus rhamnosus]
MHVAPDWLLVYKVDAEALILMFLATGTHRDTLNIE

Download         Length: 108 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10323.01 Da        Isoelectric Point: 10.7322

>AT254062 WP_005684270.1 NZ_CP102712:c616940-616668 [Lacticaseibacillus rhamnosus]
MAKESRIRNWINTITRKRALHVLNRLGLERFSAINMYWKRIGDTGALPFTLEMSFADQLRFAEADVKAGRIKSFKTVGAL
MKDLYSDVDG

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A807RQZ2

References