253892

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 911100..911754 Replicon plasmid pSOD02
Accession NZ_CP102605
Organism Pantoea sp. SOD02

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NR302_RS23620 Protein ID WP_258145884.1
Coordinates 911425..911754 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NR302_RS23615 Protein ID WP_258145522.1
Coordinates 911100..911396 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NR302_RS23575 (NR302_23575) 906128..906859 + 732 WP_154182668.1 SDR family oxidoreductase -
NR302_RS23580 (NR302_23580) 906904..907590 - 687 WP_258145521.1 DJ-1/PfpI family protein -
NR302_RS23585 (NR302_23585) 907642..908610 - 969 WP_081113251.1 magnesium/cobalt transporter CorA -
NR302_RS23590 (NR302_23590) 908654..909124 - 471 WP_008109208.1 GNAT family N-acetyltransferase -
NR302_RS23595 (NR302_23595) 909193..909435 + 243 WP_258145883.1 GNAT family N-acetyltransferase -
NR302_RS23600 (NR302_23600) 909417..909737 - 321 WP_008109204.1 AzlD domain-containing protein -
NR302_RS23605 (NR302_23605) 909727..910401 - 675 WP_008109202.1 AzlC family ABC transporter permease -
NR302_RS23610 (NR302_23610) 910504..911052 + 549 WP_061719009.1 XRE family transcriptional regulator -
NR302_RS23615 (NR302_23615) 911100..911396 - 297 WP_258145522.1 NadS family protein Antitoxin
NR302_RS23620 (NR302_23620) 911425..911754 - 330 WP_258145884.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NR302_RS23625 (NR302_23625) 911951..912472 + 522 WP_154156629.1 GNAT family N-acetyltransferase -
NR302_RS23630 (NR302_23630) 912469..913872 - 1404 WP_258145523.1 ATP-binding cassette domain-containing protein -
NR302_RS23635 (NR302_23635) 913869..914654 - 786 WP_258145524.1 ABC transporter permease subunit -
NR302_RS23640 (NR302_23640) 914651..915586 - 936 WP_258145885.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD / exeG 1..926844 926844


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(47-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-82)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12802.77 Da        Isoelectric Point: 8.4675

>T253892 WP_258145884.1 NZ_CP102605:c911754-911425 [Pantoea sp. SOD02]
ISYLEFIETRVFSKARKVLLEDDDEFNELQCYLLDHHDLGDTIRDTGGCKKIRWSRSGMGKQGGTRIIYFTRLLSGRIYL
LLIYPKNVKDDLNENEKAMLKVFTRQINL

Download         Length: 330 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11207.11 Da        Isoelectric Point: 8.6391

>AT253892 WP_258145522.1 NZ_CP102605:c911396-911100 [Pantoea sp. SOD02]
MDKKLFNDLLESMQEMVAIEKGQEIPETSRVHRHALPDVKLIRKNAGLKQAEFADAMGVSVDLIRSWEQQRRNPTGPALK
MLYLIEQQPLLINALRAI

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References