Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5210401..5210987 Replicon chromosome
Accession NZ_CP102593
Organism Xanthomonas campestris pv. phormiicola strain CFBP 8444

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag NRY95_RS22125 Protein ID WP_228320811.1
Coordinates 5210706..5210987 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NRY95_RS22120 Protein ID WP_185814804.1
Coordinates 5210401..5210691 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRY95_RS22090 (NRY95_22095) 5205757..5205966 - 210 WP_263393222.1 DUF4424 domain-containing protein -
NRY95_RS22095 (NRY95_22100) 5206414..5206986 + 573 WP_263393223.1 lysozyme inhibitor LprI family protein -
NRY95_RS22100 (NRY95_22105) 5206937..5207623 - 687 WP_263393224.1 hypothetical protein -
NRY95_RS22105 (NRY95_22110) 5208516..5208899 + 384 WP_228320813.1 BA14K family protein -
NRY95_RS22110 (NRY95_22115) 5209018..5209461 - 444 WP_228320819.1 hypothetical protein -
NRY95_RS22115 (NRY95_22120) 5209590..5210252 - 663 WP_228320812.1 hemolysin III family protein -
NRY95_RS22120 (NRY95_22125) 5210401..5210691 - 291 WP_185814804.1 HigA family addiction module antitoxin Antitoxin
NRY95_RS22125 (NRY95_22130) 5210706..5210987 - 282 WP_228320811.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NRY95_RS22130 (NRY95_22135) 5211158..5213653 + 2496 WP_228320810.1 DEAD/DEAH box helicase -
NRY95_RS22135 (NRY95_22140) 5213882..5214997 + 1116 WP_228320809.1 ribonuclease H-like domain-containing protein -
NRY95_RS22140 (NRY95_22145) 5215186..5215547 - 362 Protein_4362 saccharopine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(21-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10712.22 Da        Isoelectric Point: 9.0320

>T253878 WP_228320811.1 NZ_CP102593:c5210987-5210706 [Xanthomonas campestris pv. phormiicola]
VIRNFVDKEAEKIWQGTPSRRLPADIQAVARRKLRMLNSAAILDDLRVPPADHLEALKGNRKGQYSIRINDQSRVCFQWK
DGDALDVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10401.03 Da        Isoelectric Point: 10.5812

>AT253878 WP_185814804.1 NZ_CP102593:c5210691-5210401 [Xanthomonas campestris pv. phormiicola]
MKTLPNIHPGEVLLEEFLTPLGISQNALARAAGVPPRRINEIVLGKRSVSADSAIRLAAALGTSERFWLGLQADYDLEQA
RRALGAQARKIERIAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References