Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5036339..5036925 Replicon chromosome
Accession NZ_CP102592
Organism Xanthomonas sp. CFBP 8443

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag NUG20_RS21030 Protein ID WP_263396307.1
Coordinates 5036644..5036925 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NUG20_RS21025 Protein ID WP_263396306.1
Coordinates 5036339..5036629 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG20_RS20995 (NUG20_21000) 5032209..5032544 - 336 WP_263396300.1 thioredoxin family protein -
NUG20_RS21000 (NUG20_21005) 5032553..5032951 - 399 WP_263396301.1 host attachment family protein -
NUG20_RS21005 (NUG20_21010) 5033091..5033990 - 900 WP_263396302.1 DUF4424 domain-containing protein -
NUG20_RS21010 (NUG20_21015) 5034318..5034863 + 546 WP_263396303.1 lysozyme inhibitor LprI family protein -
NUG20_RS21015 (NUG20_21020) 5034975..5035427 - 453 WP_263396304.1 hypothetical protein -
NUG20_RS21020 (NUG20_21025) 5035529..5036185 - 657 WP_263396305.1 hemolysin III family protein -
NUG20_RS21025 (NUG20_21030) 5036339..5036629 - 291 WP_263396306.1 HigA family addiction module antitoxin Antitoxin
NUG20_RS21030 (NUG20_21035) 5036644..5036925 - 282 WP_263396307.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NUG20_RS21035 (NUG20_21040) 5037096..5039591 + 2496 WP_263396308.1 DEAD/DEAH box helicase -
NUG20_RS21040 (NUG20_21045) 5039811..5040926 + 1116 WP_263396309.1 ribonuclease H-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(21-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10777.30 Da        Isoelectric Point: 9.8794

>T253873 WP_263396307.1 NZ_CP102592:c5036925-5036644 [Xanthomonas sp. CFBP 8443]
VIRNFVDKEAEKIWQGTPSRRLPADIQVVARRKLRMLNSAATLDDLRVPPANRLEALKGDRKGQHSTRINDPWRVCFQWK
DGDALDVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10429.08 Da        Isoelectric Point: 10.5812

>AT253873 WP_263396306.1 NZ_CP102592:c5036629-5036339 [Xanthomonas sp. CFBP 8443]
MKTLPNIHPGEVLLEEFLTPLGISQNALARAAGVPPRRINEIVLGKRSITADSAIRLAAALGTSERFWLGLQADYDLEQA
RRALGAQARKIERIAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References