253813

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1731133..1731647 Replicon chromosome
Accession NZ_CP102532
Organism Limosilactobacillus fermentum strain PCC

Toxin (Protein)


Gene name yoeB Uniprot ID A0A6C1EMT8
Locus tag NUU04_RS08945 Protein ID WP_035437199.1
Coordinates 1731133..1731396 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NUU04_RS08950 Protein ID WP_035437201.1
Coordinates 1731393..1731647 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUU04_RS08930 (NUU04_08930) 1726609..1727391 + 783 WP_035437193.1 arginine deiminase-related protein -
NUU04_RS08935 (NUU04_08935) 1727779..1729176 + 1398 WP_035437196.1 Na+/H+ antiporter NhaC family protein -
NUU04_RS08940 (NUU04_08940) 1729602..1730723 + 1122 WP_080650628.1 PTS sugar transporter subunit IIC -
NUU04_RS08945 (NUU04_08945) 1731133..1731396 - 264 WP_035437199.1 Txe/YoeB family addiction module toxin Toxin
NUU04_RS08950 (NUU04_08950) 1731393..1731647 - 255 WP_035437201.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NUU04_RS08955 (NUU04_08955) 1731896..1732183 + 288 WP_041807836.1 transposase -
NUU04_RS08960 (NUU04_08960) 1732207..1733085 + 879 WP_086031809.1 IS3 family transposase -
NUU04_RS08965 (NUU04_08965) 1733401..1733862 + 462 WP_204022139.1 hypothetical protein -
NUU04_RS08970 (NUU04_08970) 1733883..1734647 + 765 WP_080650602.1 zinc ribbon domain-containing protein -
NUU04_RS08975 (NUU04_08975) 1734854..1735699 - 846 WP_086031810.1 IS3 family transposase -
NUU04_RS08980 (NUU04_08980) 1735696..1736310 - 615 WP_035431426.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(25-78)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-55)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10252.94 Da        Isoelectric Point: 10.3349

>T253813 WP_035437199.1 NZ_CP102532:c1731396-1731133 [Limosilactobacillus fermentum]
MSYAIKLKRSANKDLKKIKGSYLEKSFLQIIEQLRKDPLAPNQGFEKLVLPIKGFYSRRINIQHRLVYKVDQDTQTVIIY
SAWSHDE

Download         Length: 264 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9773.05 Da        Isoelectric Point: 4.4237

>AT253813 WP_035437201.1 NZ_CP102532:c1731647-1731393 [Limosilactobacillus fermentum]
MDQIVTPTQARKDLFKIIKRINENNEPVVIKPTRADEKSVVVIGEDDWKAIQETLFLVNHGVDKQIKERENEPLDDFDDV
WGQL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6C1EMT8

Antitoxin

Source ID Structure

References