Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3710616..3710838 Replicon chromosome
Accession NZ_CP102378
Organism Escherichia coli strain JB41

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag NR351_RS18140 Protein ID WP_000141634.1
Coordinates 3710616..3710723 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3710772..3710838 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NR351_RS18115 3705869..3706597 - 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -
NR351_RS18120 3706633..3706821 - 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
NR351_RS18125 3707094..3708665 + 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
NR351_RS18130 3708662..3708853 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
NR351_RS18135 3708850..3710529 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
NR351_RS18140 3710616..3710723 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3710772..3710838 + 67 - - Antitoxin
NR351_RS18145 3711199..3712470 + 1272 WP_001295225.1 aromatic amino acid transport family protein -
NR351_RS18150 3712500..3713504 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
NR351_RS18155 3713501..3714484 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
NR351_RS18160 3714495..3715397 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T253520 WP_000141634.1 NZ_CP102378:c3710723-3710616 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT253520 NZ_CP102378:3710772-3710838 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References