Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 6779600..6780254 Replicon chromosome
Accession NZ_CP102374
Organism Pseudomonas sp. T8

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NRG23_RS30785 Protein ID WP_038636757.1
Coordinates 6779904..6780254 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NRG23_RS30780 Protein ID WP_009049793.1
Coordinates 6779600..6779914 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRG23_RS30760 (NRG23_30760) 6775567..6776433 + 867 WP_009049796.1 sugar ABC transporter permease -
NRG23_RS30765 (NRG23_30765) 6776445..6777245 + 801 WP_007929618.1 carbohydrate ABC transporter permease -
NRG23_RS30770 (NRG23_30770) 6777256..6777528 + 273 WP_009049795.1 DUF2160 domain-containing protein -
NRG23_RS30775 (NRG23_30775) 6777692..6779434 + 1743 WP_257373220.1 ABC transporter substrate-binding protein -
NRG23_RS30780 (NRG23_30780) 6779600..6779914 - 315 WP_009049793.1 transcriptional regulator Antitoxin
NRG23_RS30785 (NRG23_30785) 6779904..6780254 - 351 WP_038636757.1 toxin Toxin
NRG23_RS30790 (NRG23_30790) 6780501..6781964 - 1464 WP_007929613.1 NADH-quinone oxidoreductase subunit NuoN -
NRG23_RS30795 (NRG23_30795) 6781972..6783504 - 1533 WP_009049790.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13987.96 Da        Isoelectric Point: 9.4183

>T253490 WP_038636757.1 NZ_CP102374:c6780254-6779904 [Pseudomonas sp. T8]
MGALFIELPPFQRHRQDYLDDELFRNLQLELLKAPEAGDLIERTDGLRKIRFVDERRHKGKRGGIRVIYYWWSGDAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11917.85 Da        Isoelectric Point: 10.6052

>AT253490 WP_009049793.1 NZ_CP102374:c6779914-6779600 [Pseudomonas sp. T8]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References