Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1258640..1259340 Replicon chromosome
Accession NZ_CP102330
Organism Burkholderia cepacia strain N3009-2YT

Toxin (Protein)


Gene name mqsR Uniprot ID U2G672
Locus tag NQK75_RS22445 Protein ID WP_021158759.1
Coordinates 1258640..1258936 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A105X490
Locus tag NQK75_RS22450 Protein ID WP_042974280.1
Coordinates 1258939..1259340 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQK75_RS22425 1254811..1255185 - 375 WP_257250756.1 hypothetical protein -
NQK75_RS22430 1255184..1256734 + 1551 WP_059484891.1 sensor domain-containing diguanylate cyclase -
NQK75_RS22435 1256978..1257253 + 276 WP_021158762.1 hypothetical protein -
NQK75_RS22440 1257496..1258536 + 1041 WP_027791639.1 succinylglutamate desuccinylase/aspartoacylase family protein -
NQK75_RS22445 1258640..1258936 + 297 WP_021158759.1 type II toxin-antitoxin system MqsR family toxin Toxin
NQK75_RS22450 1258939..1259340 + 402 WP_042974280.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NQK75_RS22455 1259658..1260218 + 561 WP_059492207.1 GNAT family N-acetyltransferase -
NQK75_RS22460 1260275..1261222 + 948 WP_021158756.1 ABC transporter substrate-binding protein -
NQK75_RS22465 1261291..1262340 + 1050 WP_257250758.1 LLM class flavin-dependent oxidoreductase -
NQK75_RS22470 1262348..1263700 + 1353 WP_257250759.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11193.01 Da        Isoelectric Point: 8.0535

>T253430 WP_021158759.1 NZ_CP102330:1258640-1258936 [Burkholderia cepacia]
MEKRRPHCKLSLVKALVESGQVRLTASAVLGARQLGFTEREALDVVMSLTDLDFHKSMTTYADHTIWQDVYRPLTVRGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14591.86 Da        Isoelectric Point: 8.8343

>AT253430 WP_042974280.1 NZ_CP102330:1258939-1259340 [Burkholderia cepacia]
MKCPACGAAKLVRDTRDIPYTYKGRSTVVRAITGEFCPACGESVLDLDEATRLGEAISEFNKQVNATIVDPNYIAKVRKK
LRLDQREAAELFGGGVNAFSRYETGKTNPPLALVKLLKILDRHPDLLAEVRAA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB U2G672

Antitoxin

Source ID Structure
AlphaFold DB A0A105X490

References