253414

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type III Classification (family/domain) cptIN/-
Location 113306..113892 Replicon chromosome
Accession NZ_CP102292
Organism [Ruminococcus] lactaris ATCC 29176

Toxin (Protein)


Gene name cptN Uniprot ID B5CQ38
Locus tag NQ541_RS00605 Protein ID WP_005611427.1
Coordinates 113306..113794 (-) Length 163 a.a.

Antitoxin (RNA)


Gene name cptI
Locus tag -
Coordinates 113847..113892 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQ541_RS00575 (NQ541_00575) 108729..109121 + 393 WP_005611436.1 VOC family protein -
NQ541_RS00580 (NQ541_00580) 109140..110504 + 1365 WP_005611433.1 MFS transporter -
NQ541_RS00585 (NQ541_00585) 110488..111450 + 963 WP_005611430.1 carbohydrate kinase -
NQ541_RS00590 (NQ541_00590) 111602..111922 - 321 WP_005611429.1 tetratricopeptide repeat protein -
NQ541_RS00595 (NQ541_00595) 111894..112880 - 987 WP_005611428.1 ATP-binding protein -
NQ541_RS00600 (NQ541_00600) 113132..113266 + 135 WP_004844681.1 hypothetical protein -
NQ541_RS00605 (NQ541_00605) 113306..113794 - 489 WP_005611427.1 hypothetical protein Toxin
- 113847..113892 - 46 - - Antitoxin
NQ541_RS00610 (NQ541_00610) 114083..115768 + 1686 WP_005611426.1 recombinase family protein -
NQ541_RS00615 (NQ541_00615) 115934..116173 + 240 Protein_118 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
NQ541_RS00620 (NQ541_00620) 116175..116582 + 408 WP_005611419.1 hypothetical protein -
NQ541_RS00625 (NQ541_00625) 116980..117615 + 636 WP_005611417.1 zinc ribbon domain-containing protein -
NQ541_RS00630 (NQ541_00630) 117771..117995 + 225 WP_005611413.1 helix-turn-helix transcriptional regulator -
NQ541_RS00635 (NQ541_00635) 118008..118712 + 705 WP_005611411.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 19149.11 Da        Isoelectric Point: 9.1905

>T253414 WP_005611427.1 NZ_CP102292:c113794-113306 [[Ruminococcus] lactaris ATCC 29176]
MIYQEGYVYHIKDEYFEKVQDSNLMQNKEGGTYRLTFYCLRDNKTSLLWMVPLSSRVEKFKAIHDKQVAKYGKCLTIVLG
EFDGKEAAFLLQNMFPIRDYYLDHIHTRNNNPVPVKHSIHREVTTHMKKIRQLHSRGKKVVFPDIDRLEQIMLAEVKDNA
AE

Download         Length: 489 bp

Antitoxin


Download         Length: 46 bp

>AT253414 NZ_CP102292:c113892-113847 [[Ruminococcus] lactaris ATCC 29176]
TCGAAAATATTGTTCGCTCACCGGAAGCGTCTAATAAATGTCCGGC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB B5CQ38

Antitoxin

Download structure file

References