Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1115103..1115755 Replicon chromosome
Accession NZ_CP102180
Organism Ralstonia solanacearum strain Bs715

Toxin (Protein)


Gene name higB Uniprot ID A0A454TTN3
Locus tag NQ321_RS04545 Protein ID WP_038962847.1
Coordinates 1115103..1115447 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NQ321_RS04550 Protein ID WP_020425351.1
Coordinates 1115444..1115755 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQ321_RS04530 1110799..1111962 - 1164 WP_011003438.1 2-methylcitrate synthase -
NQ321_RS04535 1112014..1112910 - 897 WP_020425352.1 methylisocitrate lyase -
NQ321_RS04540 1113103..1115052 + 1950 WP_118888105.1 propionate catabolism operon regulatory protein PrpR -
NQ321_RS04545 1115103..1115447 + 345 WP_038962847.1 hypothetical protein Toxin
NQ321_RS04550 1115444..1115755 + 312 WP_020425351.1 transcriptional regulator Antitoxin
NQ321_RS04555 1115895..1116704 - 810 WP_043885575.1 DUF2242 domain-containing protein -
NQ321_RS04560 1117991..1119787 + 1797 WP_118912045.1 3'-5' exonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1115103..1155304 40201


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-91)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13227.94 Da        Isoelectric Point: 8.4489

>T253291 WP_038962847.1 NZ_CP102180:1115103-1115447 [Ralstonia solanacearum]
MDATFIELPPFQRLREHYLSDDEYRALQQELLARPDAGDVIKGTGGLRKLRFSDKRRGKGKRGGLRVIDYHWDGGGQFWM
FVVYDKGEADDLSSDERKVLARLLEQEVKARSER

Download         Length: 345 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11619.65 Da        Isoelectric Point: 10.7132

>AT253291 WP_020425351.1 NZ_CP102180:1115444-1115755 [Ralstonia solanacearum]
MKRNLFAELKEGMDALAAEREGKMTLRKVKVRVLQPLDVTAEEIKAVRAAAHASQAVMARRLRVNVRTYQNWEQGTAKPN
TQAAVLIKLVEKHPETLQMLEAL

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A454TTN3

Antitoxin

Source ID Structure

References