Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1098514..1099169 Replicon chromosome
Accession NZ_CP102179
Organism Pseudomonas canavaninivorans strain B21-020

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY40_RS04795 Protein ID WP_030139927.1
Coordinates 1098514..1098858 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A923JRE9
Locus tag LOY40_RS04800 Protein ID WP_030139928.1
Coordinates 1098855..1099169 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY40_RS04770 (LOY40_04770) 1093527..1094474 + 948 WP_181287658.1 ubiquinol oxidase subunit II -
LOY40_RS04775 (LOY40_04775) 1094478..1096508 + 2031 WP_030139923.1 cytochrome o ubiquinol oxidase subunit I -
LOY40_RS04780 (LOY40_04780) 1096512..1097138 + 627 WP_030139924.1 cytochrome o ubiquinol oxidase subunit III -
LOY40_RS04785 (LOY40_04785) 1097139..1097474 + 336 WP_041022358.1 cytochrome o ubiquinol oxidase subunit IV -
LOY40_RS04790 (LOY40_04790) 1097486..1098373 + 888 WP_258648935.1 heme o synthase -
LOY40_RS04795 (LOY40_04795) 1098514..1098858 + 345 WP_030139927.1 toxin Toxin
LOY40_RS04800 (LOY40_04800) 1098855..1099169 + 315 WP_030139928.1 helix-turn-helix domain-containing protein Antitoxin
LOY40_RS04805 (LOY40_04805) 1099363..1100067 - 705 WP_258648937.1 hypothetical protein -
LOY40_RS04810 (LOY40_04810) 1100189..1100932 - 744 WP_258648938.1 DUF72 domain-containing protein -
LOY40_RS04815 (LOY40_04815) 1101009..1102022 - 1014 WP_030139931.1 sensor domain-containing diguanylate cyclase -
LOY40_RS04820 (LOY40_04820) 1102191..1103093 - 903 WP_217861283.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13804.76 Da        Isoelectric Point: 9.6383

>T253287 WP_030139927.1 NZ_CP102179:1098514-1098858 [Pseudomonas canavaninivorans]
MRTLFFETTTFTATVGHYLTDDEYRLLQFYMQQHPEAGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLRHDRQFWM
FAIYDKDELENLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11799.77 Da        Isoelectric Point: 9.8896

>AT253287 WP_030139928.1 NZ_CP102179:1098855-1099169 [Pseudomonas canavaninivorans]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDRLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References