253284

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 6078989..6079658 Replicon chromosome
Accession NZ_CP102177
Organism Pseudomonas corrugata strain B21-055

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY64_RS27220 Protein ID WP_055136377.1
Coordinates 6079293..6079658 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A3M3EAW2
Locus tag LOY64_RS27215 Protein ID WP_024779393.1
Coordinates 6078989..6079300 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY64_RS27205 (LOY64_27220) 6075033..6078776 + 3744 WP_265068323.1 bifunctional diguanylate cyclase/phosphodiesterase -
LOY64_RS27215 (LOY64_27230) 6078989..6079300 - 312 WP_024779393.1 XRE family transcriptional regulator Antitoxin
LOY64_RS27220 (LOY64_27235) 6079293..6079658 - 366 WP_055136377.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY64_RS27225 (LOY64_27240) 6079942..6082305 + 2364 WP_265068324.1 hypothetical protein -
LOY64_RS27230 (LOY64_27245) 6082342..6082803 + 462 WP_024779396.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(5-86)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14038.73 Da        Isoelectric Point: 5.5787

>T253284 WP_055136377.1 NZ_CP102177:c6079658-6079293 [Pseudomonas corrugata]
MKWDVEYTDEFEIWWNRLGESEQDSVQASVMLLGDAGPFLGFPHTSDIKGSRHGNLRELRVQHGGRPYRVLYAFDPRRCA
ILLIGGGKTGQDRWYHEYVPLAERLYDEHLEVLKKEGFDNG

Download         Length: 366 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11825.59 Da        Isoelectric Point: 9.9873

>AT253284 WP_024779393.1 NZ_CP102177:c6079300-6078989 [Pseudomonas corrugata]
MAKKFADLVARRSPDSQVRTQALYQKLRAEMPLHELRQAQELSQEALAKALHINQAAVSKMERRTDMYISTLRNYIRAMG
GELEIIATFPDGQVRIENFSHQP

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3M3EAW2

References