Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1344170..1344689 Replicon chromosome
Accession NZ_CP102149
Organism Streptococcus suis strain DNC13

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NQZ89_RS06980 Protein ID WP_257103980.1
Coordinates 1344432..1344689 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NQZ89_RS06975 Protein ID WP_172094746.1
Coordinates 1344170..1344430 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ89_RS06935 (NQZ89_06935) 1339263..1339400 + 138 WP_018368178.1 50S ribosomal protein L34 -
NQZ89_RS06940 (NQZ89_06940) 1339452..1340333 - 882 WP_172094742.1 diacylglycerol kinase family lipid kinase -
NQZ89_RS06945 (NQZ89_06945) 1340481..1341707 + 1227 WP_172079658.1 ArgE/DapE family deacylase -
NQZ89_RS06950 (NQZ89_06950) 1341730..1341954 + 225 WP_172079657.1 hypothetical protein -
NQZ89_RS06955 (NQZ89_06955) 1341938..1342720 + 783 WP_172094795.1 TatD family hydrolase -
NQZ89_RS06960 (NQZ89_06960) 1342683..1343273 + 591 WP_257103978.1 ribonuclease M5 -
NQZ89_RS06965 (NQZ89_06965) 1343266..1343634 + 369 WP_172094744.1 hypothetical protein -
NQZ89_RS06970 (NQZ89_06970) 1343639..1344094 + 456 WP_257103979.1 8-oxo-dGTP diphosphatase -
NQZ89_RS06975 (NQZ89_06975) 1344170..1344430 + 261 WP_172094746.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NQZ89_RS06980 (NQZ89_06980) 1344432..1344689 + 258 WP_257103980.1 Txe/YoeB family addiction module toxin Toxin
NQZ89_RS06985 (NQZ89_06985) 1344805..1345677 + 873 WP_257103981.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
NQZ89_RS06990 (NQZ89_06990) 1345880..1347613 + 1734 WP_257103982.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10353.83 Da        Isoelectric Point: 8.3465

>T253253 WP_257103980.1 NZ_CP102149:1344432-1344689 [Streptococcus suis]
MGIHFTDDAWEDYPYWQGQDKKTLKRINKIIKDMQRHPFEGIAKPEPLKYDYQGAWSRRIDAENRLIYMVEADQLYILSL
KDRYK

Download         Length: 258 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9948.32 Da        Isoelectric Point: 5.1255

>AT253253 WP_172094746.1 NZ_CP102149:1344170-1344430 [Streptococcus suis]
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNAYLSQKVLRGMAQVKAGQTQER
NLIEVD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References