253244

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1286082..1286601 Replicon chromosome
Accession NZ_CP102145
Organism Streptococcus suis strain DNS20

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NQZ91_RS06315 Protein ID WP_257117156.1
Coordinates 1286082..1286339 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0M9FLP3
Locus tag NQZ91_RS06320 Protein ID WP_029693536.1
Coordinates 1286341..1286601 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ91_RS06300 (NQZ91_06300) 1282548..1284278 - 1731 WP_257117154.1 hypothetical protein -
NQZ91_RS06305 (NQZ91_06305) 1284480..1285352 - 873 WP_257117155.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
NQZ91_RS06310 (NQZ91_06310) 1285364..1285996 - 633 WP_238143419.1 tetratricopeptide repeat protein -
NQZ91_RS06315 (NQZ91_06315) 1286082..1286339 - 258 WP_257117156.1 Txe/YoeB family addiction module toxin Toxin
NQZ91_RS06320 (NQZ91_06320) 1286341..1286601 - 261 WP_029693536.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NQZ91_RS06325 (NQZ91_06325) 1287116..1287571 - 456 WP_257117157.1 8-oxo-dGTP diphosphatase -
NQZ91_RS06330 (NQZ91_06330) 1287575..1287943 - 369 WP_172021035.1 hypothetical protein -
NQZ91_RS06335 (NQZ91_06335) 1287936..1288526 - 591 WP_257117158.1 ribonuclease M5 -
NQZ91_RS06340 (NQZ91_06340) 1288489..1289271 - 783 WP_257118050.1 TatD family hydrolase -
NQZ91_RS06345 (NQZ91_06345) 1289502..1290728 - 1227 WP_172079658.1 ArgE/DapE family deacylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10351.75 Da        Isoelectric Point: 6.7254

>T253244 WP_257117156.1 NZ_CP102145:c1286339-1286082 [Streptococcus suis]
MGIHFTEDAWEDYLYWQGQDKKTLKRINKIIKDTQRHPFEGIAKPEPLKYDYQGAWSRRIDAEDRLIYMVESDQLYILSL
KDHYK

Download         Length: 258 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9950.29 Da        Isoelectric Point: 5.1255

>AT253244 WP_029693536.1 NZ_CP102145:c1286601-1286341 [Streptococcus suis]
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNTYLSQKVLRGMAQVKAGQTQER
NLIEAD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0M9FLP3

References