253174

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 295279..295798 Replicon chromosome
Accession NZ_CP102089
Organism Staphylococcus capitis subsp. capitis strain H17

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NF392_RS01200 Protein ID WP_023351018.1
Coordinates 295279..295548 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NF392_RS01205 Protein ID WP_023351019.1
Coordinates 295541..295798 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF392_RS12060 290994..292145 + 1152 Protein_233 LPXTG cell wall anchor domain-containing protein -
NF392_RS01185 292259..293017 + 759 WP_002454143.1 alpha/beta hydrolase family protein -
NF392_RS01190 293558..294706 + 1149 WP_171817094.1 CapA family protein -
NF392_RS01195 294770..295135 - 366 WP_002436243.1 DUF4870 domain-containing protein -
NF392_RS01200 295279..295548 - 270 WP_023351018.1 Txe/YoeB family addiction module toxin Toxin
NF392_RS01205 295541..295798 - 258 WP_023351019.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NF392_RS01210 295983..296840 + 858 WP_023351020.1 ABC transporter substrate-binding protein -
NF392_RS01215 296955..298595 - 1641 WP_260832860.1 alpha-keto acid decarboxylase family protein -
NF392_RS01220 298768..299223 + 456 WP_002436214.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10500.96 Da        Isoelectric Point: 9.7884

>T253174 WP_023351018.1 NZ_CP102089:c295548-295279 [Staphylococcus capitis subsp. capitis]
MSKFSVAFTAQAFKDYQYWQQHNQNYFKKVNSLLKSIARDGCVDGIGKPEALKGNYEGYFSRRVSIEQRLIYKIKDDSIF
VVSCRFHYQ

Download         Length: 270 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9722.82 Da        Isoelectric Point: 4.1359

>AT253174 WP_023351019.1 NZ_CP102089:c295798-295541 [Staphylococcus capitis subsp. capitis]
MPSVNYSNARQNFKELITKVNEDSVAYTITTKENENAVILAEKDYNAMLETMYLLSNLANVSHLNQSIMELNHNQTITIE
IDDNE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References