Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2207851..2208370 Replicon chromosome
Accession NZ_CP102087
Organism Staphylococcus capitis subsp. capitis strain K1-2-2-23

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NF398_RS10855 Protein ID WP_023351018.1
Coordinates 2208101..2208370 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NF398_RS10850 Protein ID WP_023351019.1
Coordinates 2207851..2208108 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF398_RS10835 2204426..2204881 - 456 WP_002436214.1 MarR family transcriptional regulator -
NF398_RS10840 2205054..2206694 + 1641 WP_023351021.1 alpha-keto acid decarboxylase family protein -
NF398_RS10845 2206809..2207666 - 858 WP_023351020.1 ABC transporter substrate-binding protein -
NF398_RS10850 2207851..2208108 + 258 WP_023351019.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NF398_RS10855 2208101..2208370 + 270 WP_023351018.1 Txe/YoeB family addiction module toxin Toxin
NF398_RS10860 2208514..2208879 + 366 WP_002436243.1 DUF4870 domain-containing protein -
NF398_RS10865 2208943..2210091 - 1149 WP_171817094.1 CapA family protein -
NF398_RS10870 2210632..2211390 - 759 WP_002454143.1 alpha/beta hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10500.96 Da        Isoelectric Point: 9.7884

>T253173 WP_023351018.1 NZ_CP102087:2208101-2208370 [Staphylococcus capitis subsp. capitis]
MSKFSVAFTAQAFKDYQYWQQHNQNYFKKVNSLLKSIARDGCVDGIGKPEALKGNYEGYFSRRVSIEQRLIYKIKDDSIF
VVSCRFHYQ

Download         Length: 270 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9722.82 Da        Isoelectric Point: 4.1359

>AT253173 WP_023351019.1 NZ_CP102087:2207851-2208108 [Staphylococcus capitis subsp. capitis]
MPSVNYSNARQNFKELITKVNEDSVAYTITTKENENAVILAEKDYNAMLETMYLLSNLANVSHLNQSIMELNHNQTITIE
IDDNE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References