Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 5176517..5177307 Replicon chromosome
Accession NZ_CP101910
Organism Pseudomonas putida strain ATCC 12633

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag NP430_RS23245 Protein ID WP_016497991.1
Coordinates 5176840..5177307 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID I7C311
Locus tag NP430_RS23240 Protein ID WP_014859917.1
Coordinates 5176517..5176843 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP430_RS23220 (NP430_23220) 5172054..5173115 - 1062 WP_016497995.1 HlyD family secretion protein -
NP430_RS23225 (NP430_23225) 5173144..5174685 - 1542 WP_016497994.1 MFS transporter -
NP430_RS23230 (NP430_23230) 5174802..5175707 - 906 WP_016497993.1 LysR family transcriptional regulator -
NP430_RS23235 (NP430_23235) 5175978..5176424 + 447 WP_016497992.1 universal stress protein -
NP430_RS23240 (NP430_23240) 5176517..5176843 + 327 WP_014859917.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
NP430_RS23245 (NP430_23245) 5176840..5177307 + 468 WP_016497991.1 type II toxin-antitoxin system YhaV family toxin Toxin
NP430_RS23250 (NP430_23250) 5177380..5178240 - 861 WP_016497990.1 HlyD family secretion protein -
NP430_RS23255 (NP430_23255) 5178251..5178451 - 201 WP_009685040.1 DUF1656 domain-containing protein -
NP430_RS23260 (NP430_23260) 5178441..5180618 - 2178 WP_041167558.1 FUSC family protein -
NP430_RS23265 (NP430_23265) 5180615..5182144 - 1530 WP_016497988.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(17-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17879.27 Da        Isoelectric Point: 9.6727

>T252887 WP_016497991.1 NZ_CP101910:5176840-5177307 [Pseudomonas putida]
MSDASRKPLVIHGWTVIAHPLFLAKLDALSAQVEAQRDKDPTGYTRRNAFKRLAAIRRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRACESSDDAYKVFQKMLHGGHPPDDWDQLLQEAAAD

Download         Length: 468 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11919.40 Da        Isoelectric Point: 4.3722

>AT252887 WP_014859917.1 NZ_CP101910:5176517-5176843 [Pseudomonas putida]
MAATFDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGGVILTRAEATEDDPVLGKFLDFLAHDIATNPQRLQVV
DAGLIARLDKLVGDAEVDLDQPLSADDE

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I7C311

References