Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 5759083..5759705 Replicon chromosome
Accession NZ_CP101752
Organism Pseudomonas citronellolis strain C12

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NOX82_RS25225 Protein ID WP_116422899.1
Coordinates 5759083..5759397 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NOX82_RS25230 Protein ID WP_116422898.1
Coordinates 5759400..5759705 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOX82_RS25215 (NOX82_25215) 5754565..5756904 - 2340 WP_256512556.1 AAA family ATPase -
NOX82_RS25220 (NOX82_25220) 5757990..5758706 + 717 WP_256512558.1 hypothetical protein -
NOX82_RS25225 (NOX82_25225) 5759083..5759397 + 315 WP_116422899.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NOX82_RS25230 (NOX82_25230) 5759400..5759705 + 306 WP_116422898.1 helix-turn-helix domain-containing protein Antitoxin
NOX82_RS25235 (NOX82_25235) 5759892..5761337 + 1446 WP_256512561.1 SulP family inorganic anion transporter -
NOX82_RS25240 (NOX82_25240) 5761428..5761754 + 327 WP_249919006.1 hypothetical protein -
NOX82_RS25245 (NOX82_25245) 5761848..5763389 - 1542 WP_256512564.1 cyclic diguanylate phosphodiesterase -
NOX82_RS25250 (NOX82_25250) 5763558..5764070 + 513 WP_256512566.1 RDD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-72)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11779.49 Da        Isoelectric Point: 8.5126

>T252605 WP_116422899.1 NZ_CP101752:5759083-5759397 [Pseudomonas citronellolis]
MIFIETPVFTRQILELVDDETYRRLQEDLTLHPDAGAVIAGTGGVRKIRIAANGHGKRGGARVIYYHFVSASHIAFLLAY
DKATQEDLTADQKKVLRQIIENWR

Download         Length: 315 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11281.79 Da        Isoelectric Point: 7.3221

>AT252605 WP_116422898.1 NZ_CP101752:5759400-5759705 [Pseudomonas citronellolis]
MDKELFAELVESVTQMDEIVRGERQPSREFHVDALKVREIRRATGLSQAKFAEKINVAVGTLRNWEQGRRDPEGPARALL
QAIHNDPVHVLAALNGGPSKN

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References