Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 335209..335798 Replicon chromosome
Accession NZ_CP101703
Organism Xanthomonas oryzae pv. oryzae strain CIX4506

Toxin (Protein)


Gene name graT Uniprot ID G7TIR7
Locus tag NO458_RS01495 Protein ID WP_012443754.1
Coordinates 335209..335490 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NO458_RS01500 Protein ID WP_011260746.1
Coordinates 335508..335798 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NO458_RS01490 (NO458_01490) 332862..335114 + 2253 WP_012443753.1 exodeoxyribonuclease V subunit alpha -
NO458_RS01495 (NO458_01495) 335209..335490 + 282 WP_012443754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NO458_RS01500 (NO458_01500) 335508..335798 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
NO458_RS01505 (NO458_01505) 336727..338121 + 1395 WP_027703652.1 type III secretion system effector XopQ -
NO458_RS01510 (NO458_01510) 338224..338411 - 188 Protein_296 hypothetical protein -
NO458_RS01515 (NO458_01515) 338571..338903 - 333 WP_011260743.1 hypothetical protein -
NO458_RS01520 (NO458_01520) 339158..339463 + 306 WP_224229802.1 hypothetical protein -
NO458_RS01525 (NO458_01525) 339613..340035 + 423 WP_033013301.1 PAAR domain-containing protein -
NO458_RS01530 (NO458_01530) 340038..340514 + 477 WP_011260741.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11066.83 Da        Isoelectric Point: 10.5318

>T252516 WP_012443754.1 NZ_CP101703:335209-335490 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT252516 WP_011260746.1 NZ_CP101703:335508-335798 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GFW5

Antitoxin

Source ID Structure

References