Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 335220..335809 Replicon chromosome
Accession NZ_CP101702
Organism Xanthomonas oryzae pv. oryzae strain CIX4509

Toxin (Protein)


Gene name graT Uniprot ID G7TIR7
Locus tag NO460_RS01480 Protein ID WP_012443754.1
Coordinates 335220..335501 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NO460_RS01485 Protein ID WP_011260746.1
Coordinates 335519..335809 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NO460_RS01475 (NO460_01475) 332873..335125 + 2253 WP_012443753.1 exodeoxyribonuclease V subunit alpha -
NO460_RS01480 (NO460_01480) 335220..335501 + 282 WP_012443754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NO460_RS01485 (NO460_01485) 335519..335809 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
NO460_RS01490 (NO460_01490) 336738..338132 + 1395 WP_027703652.1 type III secretion system effector XopQ -
NO460_RS01495 (NO460_01495) 338235..338422 - 188 Protein_293 hypothetical protein -
NO460_RS01500 (NO460_01500) 338582..338914 - 333 WP_011260743.1 hypothetical protein -
NO460_RS01505 (NO460_01505) 339169..339474 + 306 WP_224229802.1 hypothetical protein -
NO460_RS01510 (NO460_01510) 339624..340046 + 423 WP_033013301.1 PAAR domain-containing protein -
NO460_RS01515 (NO460_01515) 340049..340525 + 477 WP_011260741.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11066.83 Da        Isoelectric Point: 10.5318

>T252512 WP_012443754.1 NZ_CP101702:335220-335501 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT252512 WP_011260746.1 NZ_CP101702:335519-335809 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GFW5

Antitoxin

Source ID Structure

References