Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/-
Location 208653..209323 Replicon chromosome
Accession NZ_CP101613
Organism Erwinia persicina strain SR15

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag NOG67_RS00920 Protein ID WP_245006705.1
Coordinates 208985..209323 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag NOG67_RS00915 Protein ID WP_062748154.1
Coordinates 208653..208967 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOG67_RS00890 (NOG67_00885) 204072..204980 - 909 WP_062749615.1 LysR family transcriptional regulator -
NOG67_RS00895 (NOG67_00890) 205111..205752 + 642 WP_118665260.1 hydrolase -
NOG67_RS00900 (NOG67_00895) 205792..206376 + 585 WP_062748150.1 antibiotic biosynthesis monooxygenase -
NOG67_RS00905 (NOG67_00900) 206366..208237 + 1872 WP_187510283.1 amidohydrolase -
NOG67_RS00910 (NOG67_00905) 208342..208668 + 327 WP_244634686.1 helix-turn-helix transcriptional regulator -
NOG67_RS00915 (NOG67_00910) 208653..208967 + 315 WP_062748154.1 HipA N-terminal domain-containing protein Antitoxin
NOG67_RS00920 (NOG67_00915) 208985..209323 + 339 WP_245006705.1 HipA domain-containing protein Toxin
NOG67_RS00925 (NOG67_00920) 209265..209645 + 381 WP_240343549.1 hypothetical protein -
NOG67_RS00930 (NOG67_00925) 209663..210523 - 861 WP_162901003.1 hypothetical protein -
NOG67_RS00935 (NOG67_00930) 210547..211524 - 978 WP_255851330.1 hypothetical protein -
NOG67_RS00940 (NOG67_00935) 211707..212627 + 921 WP_240043791.1 substrate-binding domain-containing protein -
NOG67_RS00945 (NOG67_00940) 213305..213934 + 630 WP_137269202.1 common pilus major fimbrillin subunit EcpA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12331.20 Da        Isoelectric Point: 7.9893

>T252376 WP_245006705.1 NZ_CP101613:208985-209323 [Erwinia persicina]
MTPLKSERERALGYATKGLKMLTGLARVEPQLTFTRAQFVQYLPKEQQGMSISGYQPKLQMVMEDGAFAVVESKGNYILK
PSPVDFPQLAENEHDADGAAGIRCTATRPVTL

Download         Length: 339 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12184.96 Da        Isoelectric Point: 8.4054

>AT252376 WP_062748154.1 NZ_CP101613:208653-208967 [Erwinia persicina]
MRRRLTVWLYGEPVGWLTQNDEGYLFEYRPDYAGPPLSLSLPVDKKRFPRNTLHPYFASLAPEGWLKRRYSQLQKIDEQD
LLGMLLHNGENLIGAVRLSVEEPR

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References