Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 901664..902316 Replicon chromosome
Accession NZ_CP101527
Organism Alkalimarinus sediminis strain FA028

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NNL22_RS04115 Protein ID WP_251810397.1
Coordinates 901664..902005 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NNL22_RS04120 Protein ID WP_251810396.1
Coordinates 902005..902316 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NNL22_RS04080 (NNL22_04080) 897127..897492 - 366 Protein_793 methionine-R-sulfoxide reductase -
NNL22_RS04090 (NNL22_04090) 898152..898508 + 357 WP_251810402.1 rhodanese-like domain-containing protein -
NNL22_RS04095 (NNL22_04095) 898522..899226 + 705 WP_251810401.1 DsbA family protein -
NNL22_RS04100 (NNL22_04100) 899287..900261 + 975 WP_251810400.1 arsenosugar biosynthesis radical SAM protein ArsS -
NNL22_RS04105 (NNL22_04105) 900268..900948 + 681 WP_251810399.1 TIGR04283 family arsenosugar biosynthesis glycosyltransferase -
NNL22_RS04110 (NNL22_04110) 900984..901595 + 612 WP_251810398.1 TIGR04282 family arsenosugar biosynthesis glycosyltransferase -
NNL22_RS04115 (NNL22_04115) 901664..902005 + 342 WP_251810397.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NNL22_RS04120 (NNL22_04120) 902005..902316 + 312 WP_251810396.1 transcriptional regulator Antitoxin
NNL22_RS04125 (NNL22_04125) 902366..904360 - 1995 WP_251810395.1 hypothetical protein -
NNL22_RS18730 904585..906684 - 2100 WP_275116340.1 flagellin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13586.60 Da        Isoelectric Point: 10.4546

>T252204 WP_251810397.1 NZ_CP101527:901664-902005 [Alkalimarinus sediminis]
MKAVFVELPPFERVRKDYWDDNTFRNFQNEMLNNPFSGDVIKGTGGLRKVRFRDEKRRKGKRGGVRVIYYWWKEGAQFWL
FTIYGKDEVTDLTNAERKLLAELLRHEIQVRSL

Download         Length: 342 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11859.63 Da        Isoelectric Point: 10.1983

>AT252204 WP_251810396.1 NZ_CP101527:902005-902316 [Alkalimarinus sediminis]
MKRNLFEELNEGLQSLRDDREGKVTLKQHTVTAVNPPQVTSEELVSLRERLQLSQAVFAGFLRINKRTLENWEQGRVKPN
SQAALLIKMVEKYPDTIQRLGTI

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References