Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 205794..206319 Replicon chromosome
Accession NZ_CP101497
Organism Microcella sp. MMS21-STM10

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NNL39_RS00910 Protein ID WP_255159844.1
Coordinates 206059..206319 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NNL39_RS00905 Protein ID WP_255159843.1
Coordinates 205794..206045 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NNL39_RS00880 (NNL39_00880) 201209..202075 + 867 WP_255159838.1 transporter substrate-binding domain-containing protein -
NNL39_RS00885 (NNL39_00885) 202075..202947 + 873 WP_255159839.1 amino acid ABC transporter permease -
NNL39_RS00890 (NNL39_00890) 202944..203684 + 741 WP_255159840.1 amino acid ABC transporter ATP-binding protein -
NNL39_RS00895 (NNL39_00895) 203681..204523 - 843 WP_255159841.1 ADP/ATP-dependent (S)-NAD(P)H-hydrate dehydratase -
NNL39_RS00900 (NNL39_00900) 204595..205734 + 1140 WP_255159842.1 NADH:flavin oxidoreductase/NADH oxidase -
NNL39_RS00905 (NNL39_00905) 205794..206045 + 252 WP_255159843.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NNL39_RS00910 (NNL39_00910) 206059..206319 + 261 WP_255159844.1 Txe/YoeB family addiction module toxin Toxin
NNL39_RS00915 (NNL39_00915) 206358..207005 - 648 WP_255159845.1 hypothetical protein -
NNL39_RS00920 (NNL39_00920) 207041..208090 - 1050 WP_255159846.1 hemolysin family protein -
NNL39_RS00925 (NNL39_00925) 208087..209433 - 1347 WP_255159847.1 hemolysin family protein -
NNL39_RS00930 (NNL39_00930) 209564..211003 - 1440 WP_255159848.1 GuaB1 family IMP dehydrogenase-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10150.56 Da        Isoelectric Point: 8.5219

>T252158 WP_255159844.1 NZ_CP101497:206059-206319 [Microcella sp. MMS21-STM10]
MSRTVAFDPHGWEDYVYWQSQDRKTLKRINLLITDALRDPFAGIGKPEPLKHILSGAWSRRVDDVNRLVYFVTDDHIVIL
QARQHY

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9174.25 Da        Isoelectric Point: 5.0618

>AT252158 WP_255159843.1 NZ_CP101497:205794-206045 [Microcella sp. MMS21-STM10]
MTAISATEARKTLFGLIQQVNDDHTAVEVVSKHGNAVILSKADYDAMTETAYLLRNPASAERLLASIERARRGEFEQHTL
TDD

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References