Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 989346..989605 Replicon chromosome
Accession NZ_CP101472
Organism Staphylococcus equorum strain DX2

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag NMQ06_RS04690 Protein ID WP_002511402.1
Coordinates 989346..989453 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 989443..989605 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMQ06_RS04660 (NMQ06_04655) 984578..985450 + 873 WP_002507156.1 ABC transporter ATP-binding protein -
NMQ06_RS04665 (NMQ06_04660) 985450..986178 + 729 WP_002507157.1 ABC transporter permease subunit -
NMQ06_RS04670 (NMQ06_04665) 986261..986821 - 561 WP_002507158.1 thioredoxin family protein -
NMQ06_RS04675 (NMQ06_04670) 987037..987477 + 441 WP_231111012.1 hypothetical protein -
NMQ06_RS04680 (NMQ06_04675) 987572..988132 + 561 WP_002511403.1 DUF1700 domain-containing protein -
NMQ06_RS04685 (NMQ06_04680) 988129..988980 + 852 WP_021339982.1 DUF4097 family beta strand repeat-containing protein -
NMQ06_RS04690 (NMQ06_04685) 989346..989453 + 108 WP_002511402.1 putative holin-like toxin Toxin
- 989443..989605 - 163 - - Antitoxin
NMQ06_RS04695 (NMQ06_04690) 989741..989911 - 171 WP_255157135.1 hypothetical protein -
NMQ06_RS04700 (NMQ06_04695) 990219..991259 - 1041 WP_021339984.1 C45 family autoproteolytic acyltransferase/hydolase -
NMQ06_RS04705 (NMQ06_04700) 991754..991924 + 171 WP_002507168.1 hypothetical protein -
NMQ06_RS04710 992028..992150 + 123 WP_255157137.1 hypothetical protein -
NMQ06_RS04715 (NMQ06_04705) 992143..992322 + 180 WP_064782806.1 hypothetical protein -
NMQ06_RS04720 (NMQ06_04710) 992377..992787 - 411 WP_002507169.1 YolD-like family protein -
NMQ06_RS04725 (NMQ06_04715) 992964..994001 + 1038 WP_021339833.1 lactonase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(4-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3756.72 Da        Isoelectric Point: 10.4997

>T252155 WP_002511402.1 NZ_CP101472:989346-989453 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Download         Length: 108 bp

Antitoxin


Download         Length: 163 bp

>AT252155 NZ_CP101472:c989605-989443 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References