Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 303339..303847 Replicon plasmid pDND3A
Accession NZ_CP101468
Organism Rhodococcus gordoniae strain DND3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NMQ04_RS22305 Protein ID WP_255163143.1
Coordinates 303587..303847 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NMQ04_RS22300 Protein ID WP_255163141.1
Coordinates 303339..303590 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMQ04_RS22275 (NMQ04_22235) 299605..300361 + 757 Protein_254 transposase -
NMQ04_RS22280 (NMQ04_22240) 300812..301081 - 270 WP_255163138.1 hypothetical protein -
NMQ04_RS22285 (NMQ04_22245) 301078..301302 - 225 WP_255163140.1 hypothetical protein -
NMQ04_RS22290 (NMQ04_22250) 301428..301643 + 216 WP_255163177.1 transposase -
NMQ04_RS22295 (NMQ04_22255) 301963..303105 - 1143 WP_255163178.1 IS701 family transposase -
NMQ04_RS22300 (NMQ04_22260) 303339..303590 + 252 WP_255163141.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NMQ04_RS22305 (NMQ04_22265) 303587..303847 + 261 WP_255163143.1 Txe/YoeB family addiction module toxin Toxin
NMQ04_RS22310 (NMQ04_22270) 304007..305536 - 1530 WP_255163145.1 hypothetical protein -
NMQ04_RS22315 (NMQ04_22275) 305533..305670 - 138 WP_255163146.1 hypothetical protein -
NMQ04_RS22320 (NMQ04_22280) 305768..306472 - 705 WP_255163148.1 hypothetical protein -
NMQ04_RS22330 (NMQ04_22290) 308210..308635 - 426 WP_255163151.1 cold shock domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..385072 385072
- inside IScluster/Tn - - 301963..312841 10878


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10345.71 Da        Isoelectric Point: 8.0599

>T252152 WP_255163143.1 NZ_CP101468:303587-303847 [Rhodococcus gordoniae]
MKLVWDESAWEDYLWWQTQDRKVLKRINTLIKDVERGGNEGIGKPEPLKHGFHGYWSRRITDEHRLVYKIGEDEIRIAAC
RYHYGS

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9399.53 Da        Isoelectric Point: 4.6794

>AT252152 WP_255163141.1 NZ_CP101468:303339-303590 [Rhodococcus gordoniae]
VKTMTYSESRARYAETLNAVTDDREEVVITRAGHEPVVMVALDDYESLKETAYLLRSPENARRLLASIDRLERGAGTTRD
LLE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References