Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 7020292..7020800 Replicon chromosome
Accession NZ_CP101397
Organism Streptomyces cavourensis strain F2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag NLU04_RS30285 Protein ID WP_255239872.1
Coordinates 7020540..7020800 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NLU04_RS30280 Protein ID WP_255239871.1
Coordinates 7020292..7020543 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLU04_RS30270 (NLU04_30210) 7016057..7018030 - 1974 WP_255239870.1 PQQ-binding-like beta-propeller repeat protein -
NLU04_RS30275 (NLU04_30215) 7018335..7020158 - 1824 WP_119824883.1 ABC-F family ATP-binding cassette domain-containing protein -
NLU04_RS30280 (NLU04_30220) 7020292..7020543 + 252 WP_255239871.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NLU04_RS30285 (NLU04_30225) 7020540..7020800 + 261 WP_255239872.1 Txe/YoeB family addiction module toxin Toxin
NLU04_RS30290 (NLU04_30230) 7020788..7022233 - 1446 WP_255239873.1 acyltransferase family protein -
NLU04_RS30295 (NLU04_30235) 7022480..7023235 + 756 WP_255239874.1 hypothetical protein -
NLU04_RS30300 (NLU04_30240) 7023274..7023945 - 672 WP_255239875.1 XRE family transcriptional regulator -
NLU04_RS30305 (NLU04_30245) 7024053..7024763 + 711 WP_175512774.1 class I SAM-dependent methyltransferase -
NLU04_RS30310 (NLU04_30250) 7024805..7025302 + 498 WP_119824893.1 DinB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10392.75 Da        Isoelectric Point: 9.0721

>T252133 WP_255239872.1 NZ_CP101397:7020540-7020800 [Streptomyces cavourensis]
VKFVWDQSSWDDCVWWQNQDRKILKRINTLLQDIARNGNEGMGKPEPLKHGFQGYWSRRITDEHRLIYKVVDDEVRVAAC
RYHYGR

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9314.43 Da        Isoelectric Point: 4.5559

>AT252133 WP_255239871.1 NZ_CP101397:7020292-7020543 [Streptomyces cavourensis]
MRTMTYTESRAKYAETLSAVVDDREEVVVTRAGHEPVVIVALDEYESLKETAYQLRSPENARRLLASIERLESGGGTVRE
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References