Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
Location | 827865..828406 | Replicon | chromosome |
Accession | NZ_CP101274 | ||
Organism | Escherichia coli strain EC21Z-014 |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | U9XPG0 |
Locus tag | NML17_RS03850 | Protein ID | WP_000615976.1 |
Coordinates | 827865..828143 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | S1EWQ0 |
Locus tag | NML17_RS03855 | Protein ID | WP_000729704.1 |
Coordinates | 828146..828406 (-) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NML17_RS03835 (825447) | 825447..826025 | + | 579 | WP_000284050.1 | D-sedoheptulose 7-phosphate isomerase | - |
NML17_RS03840 (826231) | 826231..826998 | + | 768 | WP_000333380.1 | class II glutamine amidotransferase | - |
NML17_RS03845 (826969) | 826969..827709 | - | 741 | WP_001225679.1 | peptidoglycan meso-diaminopimelic acid protein amidase | - |
NML17_RS03850 (827865) | 827865..828143 | - | 279 | WP_000615976.1 | type II toxin-antitoxin system mRNA interferase toxin YafQ | Toxin |
NML17_RS03855 (828146) | 828146..828406 | - | 261 | WP_000729704.1 | type II toxin-antitoxin system antitoxin DinJ | Antitoxin |
NML17_RS03860 (828592) | 828592..829365 | + | 774 | WP_000543895.1 | C40 family peptidase | - |
NML17_RS03865 (829422) | 829422..829778 | - | 357 | WP_001030483.1 | type II toxin-antitoxin system HicB family antitoxin | - |
NML17_RS03870 (829771) | 829771..830049 | - | 279 | WP_000598760.1 | type II toxin-antitoxin system HicA family toxin | - |
NML17_RS03875 (830154) | 830154..831866 | - | 1713 | Protein_747 | flagellar biosynthesis protein FlhA | - |
NML17_RS03880 (831838) | 831838..832623 | + | 786 | WP_000207575.1 | putative lateral flagellar export/assembly protein LafU | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | rhs/PAAR / gmhA/lpcA | 812451..830049 | 17598 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | U9XPG0 |
Antitoxin
Source | ID | Structure |
---|---|---|
PDB | 4ML0 | |
AlphaFold DB | A0A0E0Y6Z6 |