Detailed information of TA system TA251434

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1795408..1795590
• Replicon: chromosome
• Accession: NZ_CP101124
• Organism: Staphylococcus aureus subsp. aureus RN4220

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: NMK49_RS08590
• Protein ID: WP_001801861.1
• Coordinates: 1795408..1795503 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1795531..1795590 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NMK49_RS08550	1791068..1791694	+	627	WP_000669046.1	hypothetical protein	-
NMK49_RS08555	1791735..1792079	+	345	WP_000627551.1	DUF3969 family protein	-
NMK49_RS08560	1792177..1792728	+	552	WP_000414205.1	hypothetical protein	-
NMK49_RS08565	1792946..1793587	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
NMK49_RS08570	1793701..1793886	-	186	WP_000809857.1	hypothetical protein	-
NMK49_RS08575	1793888..1794064	-	177	WP_000375476.1	hypothetical protein	-
NMK49_RS08580	1794075..1794458	-	384	WP_000070812.1	hypothetical protein	-
NMK49_RS08585	1795062..1795205	-	144	WP_001549059.1	transposase	-
NMK49_RS08590	1795408..1795503	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1795531..1795590	-	60	-	-	Antitoxin
NMK49_RS08595	1795626..1795727	+	102	WP_001791893.1	hypothetical protein	-
NMK49_RS08600	1795705..1795881	-	177	Protein_1690	transposase	-
NMK49_RS08605	1796075..1796452	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T251434 WP_001801861.1 NZ_CP101124:1795408-1795503 [Staphylococcus aureus subsp. aureus RN4220]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 60 bp

>AT251434 NZ_CP101124:c1795590-1795531 [Staphylococcus aureus subsp. aureus RN4220]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin