Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2453688..2453872 Replicon chromosome
Accession NZ_CP101123
Organism Staphylococcus aureus strain MN8

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NLA26_RS12130 Protein ID WP_000482647.1
Coordinates 2453688..2453795 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2453812..2453872 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLA26_RS12105 2449050..2449523 + 474 WP_000456496.1 GyrI-like domain-containing protein -
NLA26_RS12110 2449646..2450857 - 1212 WP_001191919.1 multidrug effflux MFS transporter -
NLA26_RS12115 2451039..2451698 - 660 WP_000831298.1 membrane protein -
NLA26_RS12120 2451758..2452900 - 1143 WP_001176855.1 glycerate kinase -
NLA26_RS12125 2453168..2453554 + 387 WP_000779351.1 flippase GtxA -
NLA26_RS12130 2453688..2453795 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
NLA26_RS12135 2454443..2456206 + 1764 WP_001064829.1 ABC transporter ATP-binding protein -
NLA26_RS12140 2456231..2457964 + 1734 WP_000486505.1 ABC transporter ATP-binding protein -
NLA26_RS12145 2458195..2458362 + 168 Protein_2360 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T251425 WP_000482647.1 NZ_CP101123:2453688-2453795 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT251425 NZ_CP101123:c2453872-2453812 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References