Detailed information of TA system TA251420

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 221679..221859
• Replicon: chromosome
• Accession: NZ_CP101123
• Organism: Staphylococcus aureus strain MN8

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: NLA26_RS01440
• Protein ID: WP_001801861.1
• Coordinates: 221764..221859 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	221679..221736 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NLA26_RS01415	217092..219512	-	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-
NLA26_RS01420	220037..220479	+	443	Protein_244	DUF1433 domain-containing protein	-
NLA26_RS01425	220479..220922	+	444	WP_000731421.1	DUF1433 domain-containing protein	-
NLA26_RS01430	220922..221365	+	444	WP_001037039.1	DUF1433 domain-containing protein	-
NLA26_RS01435	221540..221641	-	102	WP_001791232.1	hypothetical protein	-
-	221679..221736	+	58	-	-	Antitoxin
NLA26_RS01440	221764..221859	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
NLA26_RS01445	222310..222756	+	447	WP_000747804.1	DUF1433 domain-containing protein	-
NLA26_RS01450	222949..223518	+	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
NLA26_RS01455	223518..224885	+	1368	WP_001093574.1	FRG domain-containing protein	-
NLA26_RS01460	225034..225606	-	573	WP_000414222.1	hypothetical protein	-
NLA26_RS01465	225704..226048	-	345	WP_000627550.1	DUF3969 family protein	-
NLA26_RS01470	226089..226715	-	627	WP_000669038.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T251420 WP_001801861.1 NZ_CP101123:c221859-221764 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT251420 NZ_CP101123:221679-221736 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin