Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 11817..12516 Replicon plasmid pRAHAQ02
Accession NC_015063
Organism Rahnella sp. Y9602

Toxin (Protein)


Gene name mqsR Uniprot ID A0A0H3FP36
Locus tag RAHAQ_RS25170 Protein ID WP_013578314.1
Coordinates 12220..12516 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A0H3FHC0
Locus tag RAHAQ_RS25165 Protein ID WP_013578313.1
Coordinates 11817..12218 (-) Length 134 a.a.

Genomic Context

RAHAQ_RS25830RAHAQ_RS25160RAHAQ_RS26930RAHAQ_RS25150RAHAQ_RS25155RAHAQ_RS27035RAHAQ_RS26925RAHAQ_RS25165RAHAQ_RS25170RAHAQ_RS25175RAHAQ_RS25180RAHAQ_RS25185RAHAQ_RS25190RAHAQ_RS25195RAHAQ_RS26940RAHAQ_RS25205RAHAQ_RS25210
Location: 7067..7936 (870 bp)
Type: Others
Protein ID: WP_013578308.1
Location: 9999..10595 (597 bp)
Type: Others
Protein ID: WP_013578311.1
Location: 13974..14210 (237 bp)
Type: Others
Protein ID: WP_148232231.1
Location: 8197..8940 (744 bp)
Type: Others
Protein ID: WP_013578309.1
Location: 9123..9881 (759 bp)
Type: Others
Protein ID: WP_013578310.1
Location: 10729..10875 (147 bp)
Type: Others
Protein ID: WP_013578312.1
Location: 11263..11454 (192 bp)
Type: Others
Protein ID: WP_148232229.1
Location: 11817..12218 (402 bp)
Type: Antitoxin
Protein ID: WP_013578313.1
Location: 12220..12516 (297 bp)
Type: Toxin
Protein ID: WP_013578314.1
Location: 12611..13060 (450 bp)
Type: Others
Protein ID: WP_148232230.1
Location: 13066..13371 (306 bp)
Type: Others
Protein ID: WP_013578316.1
Location: 13374..13616 (243 bp)
Type: Others
Protein ID: WP_013578317.1
Location: 14446..14646 (201 bp)
Type: Others
Protein ID: WP_013578318.1
Location: 14688..15194 (507 bp)
Type: Others
Protein ID: WP_041689224.1
Location: 15596..15796 (201 bp)
Type: Others
Protein ID: WP_052300800.1
Location: 16431..16652 (222 bp)
Type: Others
Protein ID: WP_013578321.1
Location: 16681..17325 (645 bp)
Type: Others
Protein ID: WP_013578322.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RAHAQ_RS258307067..7936+870WP_013578308.1LysR family transcriptional regulator-
RAHAQ_RS251508197..8940-744WP_013578309.1NAD(P)-binding domain-containing protein-
RAHAQ_RS251559123..9881-759WP_013578310.1SDR family NAD(P)-dependent oxidoreductase-
RAHAQ_RS251609999..10595+597WP_013578311.1TetR/AcrR family transcriptional regulator-
RAHAQ_RS2703510729..10875-147WP_013578312.1hypothetical protein-
RAHAQ_RS2692511263..11454-192WP_148232229.1hypothetical protein-
RAHAQ_RS2516511817..12218-402WP_013578313.1type II toxin-antitoxin system MqsA family antitoxinAntitoxin
RAHAQ_RS2517012220..12516-297WP_013578314.1type II toxin-antitoxin system MqsR family toxinToxin
RAHAQ_RS2517512611..13060-450WP_148232230.1hypothetical protein-
RAHAQ_RS2518013066..13371-306WP_013578316.1hypothetical protein-
RAHAQ_RS2518513374..13616-243WP_013578317.1DUF905 family protein-
RAHAQ_RS2693013974..14210+237WP_148232231.1hypothetical protein-
RAHAQ_RS2519014446..14646-201WP_013578318.1hypothetical protein-
RAHAQ_RS2519514688..15194-507WP_041689224.1antirestriction protein ArdA-
RAHAQ_RS2694015596..15796-201WP_052300800.1hypothetical protein-
RAHAQ_RS2520516431..16652-222WP_013578321.1hypothetical protein-
RAHAQ_RS2521016681..17325-645WP_013578322.1methylase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..133486133486


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-47)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10764.41 Da        Isoelectric Point: 7.8806

>T25110 WP_013578314.1 NC_015063:c12516-12220 [Rahnella sp. Y9602]
MEKRTPHTRLHIVQGLVAAGKVKATNTALNGADDLGLTFDDMCSAILGLTAADFFKSMTTYNDHTVWQDVYRPKLSCGDV
YLKLTVSNGVLIVSFKEK

Download         Length: 297 bp

>T25110 NC_015063:c12516-12220 [Rahnella sp. Y9602]
ATGGAAAAGAGAACTCCACATACGCGCCTTCATATCGTTCAGGGACTTGTTGCAGCAGGGAAGGTGAAAGCCACCAATAC
GGCGCTCAACGGCGCGGATGATTTAGGGCTGACATTTGATGATATGTGCAGTGCGATCCTGGGATTAACGGCAGCTGATT
TTTTTAAAAGTATGACCACCTATAATGATCATACTGTCTGGCAGGACGTATACCGCCCGAAGTTGTCGTGTGGTGACGTA
TATCTAAAACTAACGGTCAGTAACGGTGTTTTGATCGTCTCATTCAAGGAGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14922.38 Da        Isoelectric Point: 8.4858

>AT25110 WP_013578313.1 NC_015063:c12218-11817 [Rahnella sp. Y9602]
MKCSVCGGAELEFGIKKVPYSFRGRKTVIEAEGDHCPACGEVVMDREQSMAYMAKVKSFKAKVIAETIEPEYIIQVRKKL
ELTQKEASEIFGGGVNAFSRYEKGKAQPHPSIIKLLRVLDHHPELLDEVRKQA

Download         Length: 402 bp

>AT25110 NC_015063:c12218-11817 [Rahnella sp. Y9602]
ATGAAATGTTCCGTTTGTGGCGGTGCAGAACTTGAGTTTGGTATCAAAAAAGTCCCTTACTCATTCCGTGGCCGTAAAAC
AGTTATCGAGGCAGAAGGTGACCACTGTCCGGCGTGTGGTGAAGTCGTGATGGATCGTGAGCAGTCTATGGCCTACATGG
CAAAGGTGAAGTCATTTAAGGCCAAAGTCATCGCGGAAACCATCGAACCTGAGTACATCATTCAGGTGCGTAAAAAACTT
GAACTCACGCAGAAAGAGGCCAGCGAGATTTTTGGCGGGGGCGTGAATGCCTTTTCGCGTTATGAAAAGGGTAAGGCACA
GCCACACCCTTCGATCATCAAACTCCTGCGCGTACTCGATCACCATCCCGAGTTATTGGATGAAGTGCGCAAACAGGCAT
AA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0H3FP36

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0H3FHC0

References