Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 11817..12516 Replicon plasmid pRAHAQ02
Accession NC_015063
Organism Rahnella sp. Y9602

Toxin (Protein)


Gene name mqsR Uniprot ID A0A0H3FP36
Locus tag RAHAQ_RS25170 Protein ID WP_013578314.1
Coordinates 12220..12516 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A0H3FHC0
Locus tag RAHAQ_RS25165 Protein ID WP_013578313.1
Coordinates 11817..12218 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RAHAQ_RS25830 7067..7936 + 870 WP_013578308.1 LysR family transcriptional regulator -
RAHAQ_RS25150 8197..8940 - 744 WP_013578309.1 NAD(P)-binding domain-containing protein -
RAHAQ_RS25155 9123..9881 - 759 WP_013578310.1 SDR family NAD(P)-dependent oxidoreductase -
RAHAQ_RS25160 9999..10595 + 597 WP_013578311.1 TetR/AcrR family transcriptional regulator -
RAHAQ_RS27035 10729..10875 - 147 WP_013578312.1 hypothetical protein -
RAHAQ_RS26925 11263..11454 - 192 WP_148232229.1 hypothetical protein -
RAHAQ_RS25165 11817..12218 - 402 WP_013578313.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
RAHAQ_RS25170 12220..12516 - 297 WP_013578314.1 type II toxin-antitoxin system MqsR family toxin Toxin
RAHAQ_RS25175 12611..13060 - 450 WP_148232230.1 hypothetical protein -
RAHAQ_RS25180 13066..13371 - 306 WP_013578316.1 hypothetical protein -
RAHAQ_RS25185 13374..13616 - 243 WP_013578317.1 DUF905 family protein -
RAHAQ_RS26930 13974..14210 + 237 WP_148232231.1 hypothetical protein -
RAHAQ_RS25190 14446..14646 - 201 WP_013578318.1 hypothetical protein -
RAHAQ_RS25195 14688..15194 - 507 WP_041689224.1 antirestriction protein ArdA -
RAHAQ_RS26940 15596..15796 - 201 WP_052300800.1 hypothetical protein -
RAHAQ_RS25205 16431..16652 - 222 WP_013578321.1 hypothetical protein -
RAHAQ_RS25210 16681..17325 - 645 WP_013578322.1 methylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..133486 133486


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-47)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10764.41 Da        Isoelectric Point: 7.8806

>T25110 WP_013578314.1 NC_015063:c12516-12220 [Rahnella sp. Y9602]
MEKRTPHTRLHIVQGLVAAGKVKATNTALNGADDLGLTFDDMCSAILGLTAADFFKSMTTYNDHTVWQDVYRPKLSCGDV
YLKLTVSNGVLIVSFKEK

Download         Length: 297 bp

>T25110 NC_015063:c12516-12220 [Rahnella sp. Y9602]
ATGGAAAAGAGAACTCCACATACGCGCCTTCATATCGTTCAGGGACTTGTTGCAGCAGGGAAGGTGAAAGCCACCAATAC
GGCGCTCAACGGCGCGGATGATTTAGGGCTGACATTTGATGATATGTGCAGTGCGATCCTGGGATTAACGGCAGCTGATT
TTTTTAAAAGTATGACCACCTATAATGATCATACTGTCTGGCAGGACGTATACCGCCCGAAGTTGTCGTGTGGTGACGTA
TATCTAAAACTAACGGTCAGTAACGGTGTTTTGATCGTCTCATTCAAGGAGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14922.38 Da        Isoelectric Point: 8.4858

>AT25110 WP_013578313.1 NC_015063:c12218-11817 [Rahnella sp. Y9602]
MKCSVCGGAELEFGIKKVPYSFRGRKTVIEAEGDHCPACGEVVMDREQSMAYMAKVKSFKAKVIAETIEPEYIIQVRKKL
ELTQKEASEIFGGGVNAFSRYEKGKAQPHPSIIKLLRVLDHHPELLDEVRKQA

Download         Length: 402 bp

>AT25110 NC_015063:c12218-11817 [Rahnella sp. Y9602]
ATGAAATGTTCCGTTTGTGGCGGTGCAGAACTTGAGTTTGGTATCAAAAAAGTCCCTTACTCATTCCGTGGCCGTAAAAC
AGTTATCGAGGCAGAAGGTGACCACTGTCCGGCGTGTGGTGAAGTCGTGATGGATCGTGAGCAGTCTATGGCCTACATGG
CAAAGGTGAAGTCATTTAAGGCCAAAGTCATCGCGGAAACCATCGAACCTGAGTACATCATTCAGGTGCGTAAAAAACTT
GAACTCACGCAGAAAGAGGCCAGCGAGATTTTTGGCGGGGGCGTGAATGCCTTTTCGCGTTATGAAAAGGGTAAGGCACA
GCCACACCCTTCGATCATCAAACTCCTGCGCGTACTCGATCACCATCCCGAGTTATTGGATGAAGTGCGCAAACAGGCAT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3FP36

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3FHC0

References