Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 87418..88245 Replicon chromosome
Accession NC_015061
Organism Rahnella sp. Y9602

Toxin (Protein)


Gene name yhaV Uniprot ID A0A0H3F9D7
Locus tag RAHAQ_RS00410 Protein ID WP_013573434.1
Coordinates 87418..87894 (-) Length 159 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A0H3F4N7
Locus tag RAHAQ_RS00415 Protein ID WP_013573435.1
Coordinates 87901..88245 (-) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RAHAQ_RS00385 82492..83937 + 1446 WP_013573430.1 alpha/beta hydrolase -
RAHAQ_RS00390 84008..84466 + 459 WP_013573431.1 MarR family transcriptional regulator -
RAHAQ_RS00395 84601..85023 + 423 WP_013573432.1 organic hydroperoxide resistance protein -
RAHAQ_RS00400 85295..86974 + 1680 WP_013573433.1 kdo(2)-lipid A phosphoethanolamine 7''-transferase -
RAHAQ_RS00410 87418..87894 - 477 WP_013573434.1 type II toxin-antitoxin system YhaV family toxin Toxin
RAHAQ_RS00415 87901..88245 - 345 WP_013573435.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
RAHAQ_RS00420 88327..88488 - 162 WP_071882947.1 type II toxin-antitoxin system RelE/ParE family toxin -
RAHAQ_RS00425 88629..90008 - 1380 WP_013573436.1 MmgE/PrpD family protein -
RAHAQ_RS00430 90028..90807 - 780 WP_013573437.1 ABC transporter ATP-binding protein -
RAHAQ_RS00435 90807..91673 - 867 WP_013573438.1 ABC transporter ATP-binding protein -
RAHAQ_RS00440 91666..92601 - 936 WP_013573439.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(13-148)

Antitoxin

SpoVT-AbrB domain

(15-53)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 18383.17 Da        Isoelectric Point: 9.7887

>T25094 WP_013573434.1 NC_015061:c87894-87418 [Rahnella sp. Y9602]
MHNQAMEINGWTLLAHPLILQQIQALTDQVVLLRRKDPAGYKSKNATKRLAAINKLMFDVIPQDPARVEFGQGDTLGGEF
SHWFRAKFFQQYRLFFRYNLKSRIIIYAWVNDDKELRAYESKTDAYRMFRKMLKSGEPPDNWQALCEASGKVAAEELP

Download         Length: 477 bp

>T25094 NC_015061:c87894-87418 [Rahnella sp. Y9602]
ATGCACAATCAGGCCATGGAGATTAACGGATGGACCCTTCTCGCTCATCCTCTGATCCTGCAACAAATACAGGCACTCAC
TGATCAGGTTGTTTTACTGCGTCGCAAAGATCCGGCGGGCTATAAAAGTAAGAACGCCACCAAACGGCTGGCTGCGATCA
ATAAGCTGATGTTTGACGTTATCCCGCAGGATCCGGCGCGTGTTGAATTCGGTCAGGGCGATACGTTAGGCGGGGAATTC
TCACACTGGTTCAGGGCAAAATTCTTCCAGCAGTACCGTTTGTTTTTCCGCTACAACCTGAAAAGCCGGATCATTATTTA
CGCCTGGGTGAATGATGATAAAGAATTACGCGCCTACGAAAGCAAAACAGACGCATACCGGATGTTTCGCAAGATGTTGA
AAAGCGGTGAACCGCCAGACAACTGGCAGGCACTTTGCGAGGCGTCTGGGAAGGTAGCGGCGGAAGAATTACCTTAG

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12701.48 Da        Isoelectric Point: 4.3324

>AT25094 WP_013573435.1 NC_015061:c88245-87901 [Rahnella sp. Y9602]
MSASALWGIKFEAESKVTRRFQTTIPATIRKALNLTENDRIQYKILPDGQVVISRQLEEAEDPVISAFLGFVAKDMLNNP
ENMQPVTLSLHEKINVLTAGMAIDLESPLSDDDE

Download         Length: 345 bp

>AT25094 NC_015061:c88245-87901 [Rahnella sp. Y9602]
ATGTCAGCCTCGGCACTATGGGGAATAAAATTCGAAGCCGAATCCAAAGTCACCCGCCGCTTCCAGACCACCATTCCGGC
CACTATCCGTAAGGCATTAAATCTCACCGAAAATGATCGGATCCAGTACAAGATTTTGCCAGACGGGCAGGTGGTTATTT
CGAGGCAACTCGAAGAAGCGGAAGACCCTGTTATCAGTGCTTTTCTCGGTTTTGTGGCAAAAGATATGCTCAATAACCCG
GAAAATATGCAGCCGGTAACATTATCCCTGCATGAAAAAATCAATGTACTGACCGCCGGGATGGCTATCGATCTTGAGAG
CCCGCTTTCTGACGATGACGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3F9D7

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3F4N7

References