Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1070957..1071620 Replicon chromosome
Accession NZ_CP100660
Organism Pseudomonas fluorescens strain ZL22

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag NLL86_RS04770 Protein ID WP_254483337.1
Coordinates 1070957..1071286 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NLL86_RS04775 Protein ID WP_254485526.1
Coordinates 1071291..1071620 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLL86_RS04750 (NLL86_04750) 1067095..1068252 - 1158 WP_254483335.1 ABC transporter ATP-binding protein -
NLL86_RS04755 (NLL86_04755) 1068249..1068902 - 654 WP_054901077.1 ABC transporter permease -
NLL86_RS04760 (NLL86_04760) 1068899..1069813 - 915 WP_254483336.1 glycine betaine ABC transporter substrate-binding protein -
NLL86_RS04765 (NLL86_04765) 1069827..1070540 - 714 WP_054887588.1 ABC transporter permease -
NLL86_RS04770 (NLL86_04770) 1070957..1071286 + 330 WP_254483337.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLL86_RS04775 (NLL86_04775) 1071291..1071620 + 330 WP_254485526.1 XRE family transcriptional regulator Antitoxin
NLL86_RS04780 (NLL86_04780) 1071714..1073297 + 1584 WP_254483339.1 peptide chain release factor 3 -
NLL86_RS04785 (NLL86_04785) 1073330..1074409 - 1080 WP_254483341.1 polyamine ABC transporter substrate-binding protein -
NLL86_RS04790 (NLL86_04790) 1074461..1074802 - 342 WP_254483342.1 cupin domain-containing protein -
NLL86_RS04795 (NLL86_04795) 1074835..1076241 - 1407 WP_254483343.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(8-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-85)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12421.25 Da        Isoelectric Point: 7.8842

>T250914 WP_254483337.1 NZ_CP100660:1070957-1071286 [Pseudomonas fluorescens]
MCSEFVVEFSELEEVVQDELLAQLHLLKCIGPALGRPHVDTLKGSMYSNMKELRFNAAGGVWRVAFAFDRYRSALLLAAG
NKAGISERRFYRSLIDRADERFDRHLSRG

Download         Length: 330 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12408.30 Da        Isoelectric Point: 6.4813

>AT250914 WP_254485526.1 NZ_CP100660:1071291-1071620 [Pseudomonas fluorescens]
MYKTLDEVINELSPERRAKVEKRGQELIREEMTLQSLRKQLQITQEDLAKRLDIRQGNISKVESRGDMLISTLRSYLEAM
GGRLELVVHLPGRAPVSIDGIAEDPISHV

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References