Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 5272709..5273310 Replicon chromosome
Accession NZ_CP100652
Organism Pseudomonas putida strain HSM-C2

Toxin (Protein)


Gene name higB Uniprot ID A0A379KEL1
Locus tag NL778_RS24075 Protein ID WP_046788307.1
Coordinates 5272996..5273310 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NL778_RS24070 Protein ID WP_046788286.1
Coordinates 5272709..5272996 (-) Length 96 a.a.

Genomic Context

NL778_RS24060NL778_RS24065NL778_RS24080NL778_RS24085NL778_RS24070NL778_RS24075NL778_RS24090NL778_RS24095
Location: 5269546..5270463 (918 bp)
Type: Others
Protein ID: WP_254466764.1
Location: 5270483..5272237 (1755 bp)
Type: Others
Protein ID: WP_204919154.1
Location: 5273529..5274176 (648 bp)
Type: Others
Protein ID: WP_254466766.1
Location: 5274577..5276238 (1662 bp)
Type: Others
Protein ID: WP_254466767.1
Location: 5272709..5272996 (288 bp)
Type: Antitoxin
Protein ID: WP_046788286.1
Location: 5272996..5273310 (315 bp)
Type: Toxin
Protein ID: WP_046788307.1
Location: 5276356..5277675 (1320 bp)
Type: Others
Protein ID: WP_012316697.1
Location: 5278105..5278302 (198 bp)
Type: Others
Protein ID: WP_012316698.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NL778_RS24060 (NL778_24060)5269546..5270463+918WP_254466764.1sce7725 family protein-
NL778_RS24065 (NL778_24065)5270483..5272237+1755WP_204919154.1anti-phage dCTP deaminase-
NL778_RS24070 (NL778_24070)5272709..5272996-288WP_046788286.1helix-turn-helix domain-containing proteinAntitoxin
NL778_RS24075 (NL778_24075)5272996..5273310-315WP_046788307.1hypothetical proteinToxin
NL778_RS24080 (NL778_24080)5273529..5274176+648WP_254466766.1hypothetical protein-
NL778_RS24085 (NL778_24085)5274577..5276238+1662WP_254466767.1FMN-binding glutamate synthase family protein-
NL778_RS24090 (NL778_24090)5276356..5277675-1320WP_012316697.1OprD family porin-
NL778_RS24095 (NL778_24095)5278105..5278302-198WP_012316698.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11831.73 Da        Isoelectric Point: 10.1456

>T250904 WP_046788307.1 NZ_CP100652:c5273310-5272996 [Pseudomonas putida]
MIFIETPIFTQDVKEHLGDDEYRELQSYLAGQPIAGDLIEGTGGLRKIRWSAKGKGKSGGVRVIYYHVSSAYQIRMILIY
RKGIMDTLTDKQKAQLRAINKGWK

Download         Length: 315 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10804.25 Da        Isoelectric Point: 7.3222

>AT250904 WP_046788286.1 NZ_CP100652:c5272996-5272709 [Pseudomonas putida]
MEKNLFDRLVESMTQMDEIDRGERQPSREFHVDAVQVKKIRQATGLSQAAFAKRIDVAVGTLRNWEQGRREPEGPARALL
RAIHNDPEHVLAALS

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A379KEL1

Antitoxin

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Source
ID
Structure
No matching records found

References