250902

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3808511..3809211 Replicon chromosome
Accession NZ_CP100652
Organism Pseudomonas putida strain HSM-C2

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag NL778_RS17355 Protein ID WP_254466165.1
Coordinates 3808915..3809211 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag NL778_RS17350 Protein ID WP_254466164.1
Coordinates 3808511..3808912 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL778_RS17330 (NL778_17330) 3803643..3804464 - 822 WP_042111599.1 transporter substrate-binding domain-containing protein -
NL778_RS17335 (NL778_17335) 3804542..3805471 - 930 WP_012315359.1 FAD-binding protein -
NL778_RS17340 (NL778_17340) 3805472..3806221 - 750 WP_012315360.1 electron transfer flavoprotein subunit beta/FixA family protein -
NL778_RS17345 (NL778_17345) 3806778..3808442 + 1665 WP_012315361.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
NL778_RS17350 (NL778_17350) 3808511..3808912 - 402 WP_254466164.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NL778_RS17355 (NL778_17355) 3808915..3809211 - 297 WP_254466165.1 type II toxin-antitoxin system MqsR family toxin Toxin
NL778_RS17360 (NL778_17360) 3809306..3810631 - 1326 WP_254466166.1 MFS transporter -
NL778_RS17365 (NL778_17365) 3810698..3811177 - 480 WP_012315365.1 response regulator -
NL778_RS17370 (NL778_17370) 3811349..3811825 - 477 WP_012315366.1 sigma-70 family RNA polymerase sigma factor -
NL778_RS17375 (NL778_17375) 3812030..3813208 + 1179 WP_254467901.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11177.95 Da        Isoelectric Point: 8.4782

>T250902 WP_254466165.1 NZ_CP100652:c3809211-3808915 [Pseudomonas putida]
MEKRTPHCSLERIRALVSAGRISPTTASLRGAQALGMDYPDMLEIINGLERRDFQKSMTCHGDYRVWQDVYRPLTGKGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14607.74 Da        Isoelectric Point: 6.4547

>AT250902 WP_254466164.1 NZ_CP100652:c3808912-3808511 [Pseudomonas putida]
MKCPVCGGAELAPDTRDMPYRYKGEVTVIPNVSGGYCTACGEAVLSHDEAMRISPLMSAFNRQVNAAAVDPDFIVAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTRPPVALVKLFKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References