Detailed information of TA system TA250870

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2741987..2742324
• Replicon: chromosome
• Accession: NZ_CP100596
• Organism: Enterococcus faecalis strain Chr-JH 2-2

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: NLG43_RS13410
• Protein ID: WP_002411240.1
• Coordinates: 2741987..2742136 (+)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2742069..2742324 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NLG43_RS13390	2737109..2737324	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
NLG43_RS13395	2737463..2738455	+	993	WP_010817727.1	biotin--[acetyl-CoA-carboxylase] ligase	-
NLG43_RS13400	2738719..2739357	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
NLG43_RS13405	2740042..2741658	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
NLG43_RS13410	2741987..2742136	+	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	2742069..2742324	-	256	-	-	Antitoxin
NLG43_RS13415	2742327..2747018	-	4692	WP_033918128.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (16-49)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5738.05 Da
• Isoelectric Point: 11.3858

>T250870 WP_002411240.1 NZ_CP100596:2741987-2742136 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 150 bp

Antitoxin

Nucleotide

• Length: 256 bp

>AT250870 NZ_CP100596:c2742324-2742069 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATAAT
GGTGATGAAAAGAGAGGTATGTGCCAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTAGTTACAAAA
AATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAAGCA
ATGGTAAACATACCAA

Structures

Antitoxin