Detailed information of TA system TA250856

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 308656..308851
• Replicon: chromosome
• Accession: NZ_CP100596
• Organism: Enterococcus faecalis strain Chr-JH 2-2

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: NLG43_RS01545
• Protein ID: WP_015543884.1
• Coordinates: 308756..308851 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	308656..308721 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NLG43_RS01530	304289..306031	+	1743	WP_033918197.1	PTS transporter subunit EIIC	-
NLG43_RS01535	306022..308055	+	2034	WP_002361171.1	PRD domain-containing protein	-
NLG43_RS01540	308066..308500	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	308656..308721	+	66	-	-	Antitoxin
NLG43_RS01545	308756..308851	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
NLG43_RS01550	309097..310869	+	1773	WP_002387897.1	PTS mannitol-specific transporter subunit IIBC	-
NLG43_RS01555	310884..311321	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
NLG43_RS01560	311336..312490	+	1155	WP_002395429.1	mannitol-1-phosphate 5-dehydrogenase	-
NLG43_RS01565	312557..313672	-	1116	WP_033785759.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T250856 WP_015543884.1 NZ_CP100596:c308851-308756 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 66 bp

>AT250856 NZ_CP100596:308656-308721 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin