Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-ohsC/SymE(toxin)
Location 4171572..4171984 Replicon chromosome
Accession NZ_CP100530
Organism Escherichia coli strain LH10-b-1

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag NLZ08_RS20575 Protein ID WP_097749251.1
Coordinates 4171643..4171984 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name ohsC
Locus tag -
Coordinates 4171572..4171648 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ08_RS20565 (4168522) 4168522..4170111 + 1590 WP_097749252.1 type I restriction-modification system methyltransferase -
NLZ08_RS20570 (4170108) 4170108..4171415 + 1308 WP_201796878.1 restriction endonuclease subunit S -
- (4171572) 4171572..4171648 - 77 NuclAT_15 - Antitoxin
- (4171572) 4171572..4171648 - 77 NuclAT_15 - Antitoxin
- (4171572) 4171572..4171648 - 77 NuclAT_15 - Antitoxin
- (4171572) 4171572..4171648 - 77 NuclAT_15 - Antitoxin
- (4171572) 4171572..4171648 - 77 NuclAT_16 - Antitoxin
- (4171572) 4171572..4171648 - 77 NuclAT_16 - Antitoxin
- (4171572) 4171572..4171648 - 77 NuclAT_16 - Antitoxin
- (4171572) 4171572..4171648 - 77 NuclAT_16 - Antitoxin
NLZ08_RS20575 (4171643) 4171643..4171984 + 342 WP_097749251.1 endoribonuclease SymE Toxin
NLZ08_RS20580 (4172146) 4172146..4172910 + 765 Protein_4034 DUF3578 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12321.20 Da        Isoelectric Point: 8.5012

>T250795 WP_097749251.1 NZ_CP100530:4171643-4171984 [Escherichia coli]
MTDTHFIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVAVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKHKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT250795 NZ_CP100530:c4171648-4171572 [Escherichia coli]
AGTCATAACTGCTATTCTCCTGGAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References