Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 205876..206098 Replicon chromosome
Accession NZ_CP100530
Organism Escherichia coli strain LH10-b-1

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag NLZ08_RS00955 Protein ID WP_000141634.1
Coordinates 205991..206098 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 205876..205942 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLZ08_RS00930 201761..202765 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
NLZ08_RS00935 202795..204066 - 1272 WP_001295225.1 aromatic amino acid transport family protein -
NLZ08_RS00940 204542..204649 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
NLZ08_RS00945 205025..205132 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
NLZ08_RS00950 205508..205615 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
- 205876..205942 - 67 - - Antitoxin
NLZ08_RS00955 205991..206098 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
NLZ08_RS00960 206185..207864 - 1680 WP_097749325.1 cellulose biosynthesis protein BcsG -
NLZ08_RS00965 207861..208052 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
NLZ08_RS00970 208063..208533 + 471 Protein_191 cell division protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-35)


Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T250778 WP_000141634.1 NZ_CP100530:205991-206098 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp


Antitoxin


Download         Length: 67 bp

>AT250778 NZ_CP100530:c205942-205876 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
PDB 5LBJ


Antitoxin

Download structure file

References